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Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models.
Del Curatolo A, Conciatori F, Cesta Incani U, Bazzichetto C, Falcone I, Corbo V, D'Agosto S, Eramo A, Sette G, Sperduti I, De Luca T, Marabese M, Shirasawa S, De Maria R, Scarpa A, Broggini M, Del Bufalo D, Cognetti F, Milella M, Ciuffreda L. Del Curatolo A, et al. Among authors: shirasawa s. J Exp Clin Cancer Res. 2018 Jul 9;37(1):140. doi: 10.1186/s13046-018-0820-5. J Exp Clin Cancer Res. 2018. PMID: 29986755 Free PMC article.
Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17.
Van Schaeybroeck S, Kyula JN, Fenton A, Fenning CS, Sasazuki T, Shirasawa S, Longley DB, Johnston PG. Van Schaeybroeck S, et al. Among authors: shirasawa s. Cancer Res. 2011 Feb 1;71(3):1071-80. doi: 10.1158/0008-5472.CAN-10-0714. Epub 2010 Dec 10. Cancer Res. 2011. PMID: 21148749 Free PMC article.
Adrenomedullin is a therapeutic target in colorectal cancer.
Wang L, Gala M, Yamamoto M, Pino MS, Kikuchi H, Shue DS, Shirasawa S, Austin TR, Lynch MP, Rueda BR, Zukerberg LR, Chung DC. Wang L, et al. Among authors: shirasawa s. Int J Cancer. 2014 May 1;134(9):2041-50. doi: 10.1002/ijc.28542. Epub 2013 Nov 7. Int J Cancer. 2014. PMID: 24519534 Free PMC article.
Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition.
Conciatori F, Salvati E, Ciuffreda L, Shirasawa S, Falcone I, Cognetti F, Ferretti G, Zeuli M, Del Bufalo D, Bazzichetto C, Milella M. Conciatori F, et al. Among authors: shirasawa s. Front Oncol. 2022 Jun 3;12:862806. doi: 10.3389/fonc.2022.862806. eCollection 2022. Front Oncol. 2022. PMID: 35719951 Free PMC article.
241 results