Shirasaka Y - Search Results

1

Macrolide and Ketolide Antibiotics Inhibit the Cytotoxic Effect of Trastuzumab Emtansine in HER2-Positive Breast Cancer Cells: Implication of a Potential Drug-ADC Interaction in Cancer Chemotherapy.

Kiyomiya K, Tomabechi R, Saito N, Watai K, Takada T, Shirasaka Y, Kishimoto H, Higuchi K, Inoue K. Kiyomiya K, et al. Among authors: shirasaka y. Mol Pharm. 2023 Dec 4;20(12):6130-6139. doi: 10.1021/acs.molpharmaceut.3c00490. Epub 2023 Nov 16. Mol Pharm. 2023. PMID: 37971309

2

Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.

Shirasaka Y, Kawasaki M, Sakane T, Omatsu H, Moriya Y, Nakamura T, Sakaeda T, Okumura K, Langguth P, Yamashita S. Shirasaka Y, et al. Drug Metab Pharmacokinet. 2006 Oct;21(5):414-23. doi: 10.2133/dmpk.21.414. Drug Metab Pharmacokinet. 2006. PMID: 17072095 Free article.

3

The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles.

Chaudhry AS, Prasad B, Shirasaka Y, Fohner A, Finkelstein D, Fan Y, Wang S, Wu G, Aklillu E, Sim SC, Thummel KE, Schuetz EG. Chaudhry AS, et al. Among authors: shirasaka y. Drug Metab Dispos. 2015 Aug;43(8):1226-35. doi: 10.1124/dmd.115.064428. Epub 2015 May 28. Drug Metab Dispos. 2015. PMID: 26021325 Free PMC article.

4

Oseltamivir (tamiflu) is a substrate of peptide transporter 1.

Ogihara T, Kano T, Wagatsuma T, Wada S, Yabuuchi H, Enomoto S, Morimoto K, Shirasaka Y, Kobayashi S, Tamai I. Ogihara T, et al. Among authors: shirasaka y. Drug Metab Dispos. 2009 Aug;37(8):1676-81. doi: 10.1124/dmd.109.026922. Epub 2009 May 13. Drug Metab Dispos. 2009. PMID: 19439487

5

Model analysis of the concentration-dependent permeability of P-gp substrates.

Tachibana T, Kitamura S, Kato M, Mitsui T, Shirasaka Y, Yamashita S, Sugiyama Y. Tachibana T, et al. Among authors: shirasaka y. Pharm Res. 2010 Mar;27(3):442-6. doi: 10.1007/s11095-009-0026-9. Epub 2010 Feb 5. Pharm Res. 2010. PMID: 20135207

6

Expression levels of human P-glycoprotein in in vitro cell lines: correlation between mRNA and protein levels for P-glycoprotein expressed in cells.

Shirasaka Y, Konishi R, Funami N, Kadowaki Y, Nagai Y, Sakaeda T, Yamashita S. Shirasaka Y, et al. Biopharm Drug Dispos. 2009 Apr;30(3):149-52. doi: 10.1002/bdd.650. Biopharm Drug Dispos. 2009. PMID: 19243013

7

Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.

Nakamura T, Nakanishi T, Haruta T, Shirasaka Y, Keogh JP, Tamai I. Nakamura T, et al. Among authors: shirasaka y. Mol Pharm. 2010 Feb 1;7(1):187-95. doi: 10.1021/mp900206j. Mol Pharm. 2010. PMID: 20020740

8

Functional characterization of apical transporters expressed in rat proximal tubular cells (PTCs) in primary culture.

Nakanishi T, Fukushi A, Sato M, Yoshifuji M, Gose T, Shirasaka Y, Ohe K, Kobayashi M, Kawai K, Tamai I. Nakanishi T, et al. Among authors: shirasaka y. Mol Pharm. 2011 Dec 5;8(6):2142-50. doi: 10.1021/mp200096r. Epub 2011 Oct 28. Mol Pharm. 2011. PMID: 21999946

9

Absorption-Enhancing Effect of Nitric Oxide on the Absorption of Hydrophobic Drugs in Rat Duodenum.

Kishimoto H, Miyazaki K, Takizawa Y, Shirasaka Y, Inoue K. Kishimoto H, et al. Among authors: shirasaka y. J Pharm Sci. 2016 Feb;105(2):729-733. doi: 10.1002/jps.24677. Epub 2016 Jan 11. J Pharm Sci. 2016. PMID: 26458075

10

Osmolality of Orally Administered Solutions Influences Luminal Water Volume and Drug Absorption in Intestine.

Ichijo K, Oda R, Ishihara M, Okada R, Moteki Y, Funai Y, Horiuchi T, Kishimoto H, Shirasaka Y, Inoue K. Ichijo K, et al. Among authors: shirasaka y. J Pharm Sci. 2017 Sep;106(9):2889-2894. doi: 10.1016/j.xphs.2017.04.030. Epub 2017 Apr 24. J Pharm Sci. 2017. PMID: 28450238

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