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Multidisciplinary approach to the treatment of cardiac AA amyloidosis and aortic stenosis due to Castleman's disease: a hybrid therapy with tocilizumab and aortic valve replacement.
Shirakawa K, Egashira T, Ieda M, Kawaguchi S, Okamoto K, Kudo M, Yokoyama K, Tsuruta H, Murata M, Mikami S, Anzai A, Hayashida K, Kohno T, Maekawa Y, Sano M, Yozu R, Fukuda K. Shirakawa K, et al. Int J Cardiol. 2014 May 1;173(2):e9-e11. doi: 10.1016/j.ijcard.2014.03.054. Epub 2014 Mar 16. Int J Cardiol. 2014. PMID: 24681024 No abstract available.
Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart.
Matsuhashi T, Hishiki T, Zhou H, Ono T, Kaneda R, Iso T, Yamaguchi A, Endo J, Katsumata Y, Atsushi A, Yamamoto T, Shirakawa K, Yan X, Shinmura K, Suematsu M, Fukuda K, Sano M. Matsuhashi T, et al. Among authors: shirakawa k. J Mol Cell Cardiol. 2015 May;82:116-24. doi: 10.1016/j.yjmcc.2015.02.021. Epub 2015 Mar 2. J Mol Cell Cardiol. 2015. PMID: 25744081
Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Yamamoto T, Tamaki K, Shirakawa K, Ito K, Yan X, Katsumata Y, Anzai A, Matsuhashi T, Endo J, Inaba T, Tsubota K, Sano M, Fukuda K, Shinmura K. Yamamoto T, et al. Among authors: shirakawa k. Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H1003-14. doi: 10.1152/ajpheart.00676.2015. Epub 2016 Feb 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 26873964 Free article.
Obesity accelerates T cell senescence in murine visceral adipose tissue.
Shirakawa K, Yan X, Shinmura K, Endo J, Kataoka M, Katsumata Y, Yamamoto T, Anzai A, Isobe S, Yoshida N, Itoh H, Manabe I, Sekai M, Hamazaki Y, Fukuda K, Minato N, Sano M. Shirakawa K, et al. J Clin Invest. 2016 Dec 1;126(12):4626-4639. doi: 10.1172/JCI88606. Epub 2016 Nov 7. J Clin Invest. 2016. PMID: 27820698 Free PMC article.
Negative legacy of obesity.
Shirakawa K, Endo J, Katsumata Y, Yamamoto T, Kataoka M, Isobe S, Yoshida N, Fukuda K, Sano M. Shirakawa K, et al. PLoS One. 2017 Oct 26;12(10):e0186303. doi: 10.1371/journal.pone.0186303. eCollection 2017. PLoS One. 2017. PMID: 29073165 Free PMC article.
Decrease in membrane phospholipids unsaturation correlates with myocardial diastolic dysfunction.
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Yoshida N, Isobe S, Moriyama H, Goto S, Yamashita K, Nakanishi H, Shimanaka Y, Kono N, Shinmura K, Arai H, Fukuda K, Sano M. Yamamoto T, et al. Among authors: shirakawa k. PLoS One. 2018 Dec 11;13(12):e0208396. doi: 10.1371/journal.pone.0208396. eCollection 2018. PLoS One. 2018. PMID: 30533011 Free PMC article.
Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension.
Isobe S, Kataoka M, Endo J, Moriyama H, Okazaki S, Tsuchihashi K, Katsumata Y, Yamamoto T, Shirakawa K, Yoshida N, Shimoda M, Chiba T, Masuko T, Hakamata Y, Kobayashi E, Saya H, Fukuda K, Sano M. Isobe S, et al. Among authors: shirakawa k. Am J Respir Cell Mol Biol. 2019 Sep;61(3):367-379. doi: 10.1165/rcmb.2018-0231OC. Am J Respir Cell Mol Biol. 2019. PMID: 30897333
406 results