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Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro.
Shionoya K, Yamasaki M, Iwanami S, Ito Y, Fukushi S, Ohashi H, Saso W, Tanaka T, Aoki S, Kuramochi K, Iwami S, Takahashi Y, Suzuki T, Muramatsu M, Takeda M, Wakita T, Watashi K. Shionoya K, et al. Front Microbiol. 2021 Apr 30;12:651403. doi: 10.3389/fmicb.2021.651403. eCollection 2021. Front Microbiol. 2021. PMID: 33995308 Free PMC article.
Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma.
Iwanami S, Kitagawa K, Ohashi H, Asai Y, Shionoya K, Saso W, Nishioka K, Inaba H, Nakaoka S, Wakita T, Diekmann O, Iwami S, Watashi K. Iwanami S, et al. Among authors: shionoya k. PLoS Biol. 2020 Jul 30;18(7):e3000562. doi: 10.1371/journal.pbio.3000562. eCollection 2020 Jul. PLoS Biol. 2020. PMID: 32730280 Free PMC article.
Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment.
Ohashi H, Watashi K, Saso W, Shionoya K, Iwanami S, Hirokawa T, Shirai T, Kanaya S, Ito Y, Kim KS, Nomura T, Suzuki T, Nishioka K, Ando S, Ejima K, Koizumi Y, Tanaka T, Aoki S, Kuramochi K, Suzuki T, Hashiguchi T, Maenaka K, Matano T, Muramatsu M, Saijo M, Aihara K, Iwami S, Takeda M, McKeating JA, Wakita T. Ohashi H, et al. Among authors: shionoya k. iScience. 2021 Apr 23;24(4):102367. doi: 10.1016/j.isci.2021.102367. Epub 2021 Mar 26. iScience. 2021. PMID: 33817567 Free PMC article.
Different efficacies of neutralizing antibodies and antiviral drugs on SARS-CoV-2 Omicron subvariants, BA.1 and BA.2.
Ohashi H, Hishiki T, Akazawa D, Kim KS, Woo J, Shionoya K, Tsuchimoto K, Iwanami S, Moriyama S, Kinoshita H, Yamada S, Kuroda Y, Yamamoto T, Kishida N, Watanabe S, Hasegawa H, Ebihara H, Suzuki T, Maeda K, Fukushi S, Takahashi Y, Iwami S, Watashi K. Ohashi H, et al. Among authors: shionoya k. Antiviral Res. 2022 Sep;205:105372. doi: 10.1016/j.antiviral.2022.105372. Epub 2022 Jul 4. Antiviral Res. 2022. PMID: 35798223 Free PMC article.
Potential Anti-Mpox Virus Activity of Atovaquone, Mefloquine, and Molnupiravir, and Their Potential Use as Treatments.
Akazawa D, Ohashi H, Hishiki T, Morita T, Iwanami S, Kim KS, Jeong YD, Park ES, Kataoka M, Shionoya K, Mifune J, Tsuchimoto K, Ojima S, Azam AH, Nakajima S, Park H, Yoshikawa T, Shimojima M, Kiga K, Iwami S, Maeda K, Suzuki T, Ebihara H, Takahashi Y, Watashi K. Akazawa D, et al. Among authors: shionoya k. J Infect Dis. 2023 Aug 31;228(5):591-603. doi: 10.1093/infdis/jiad058. J Infect Dis. 2023. PMID: 36892247 Free PMC article.
An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity.
Wing PAC, Schmidt NM, Peters R, Erdmann M, Brown R, Wang H, Swadling L; COVIDsortium Investigators; Newman J, Thakur N, Shionoya K, Morgan SB, Hinks TS, Watashi K, Bailey D, Hansen SB, Davidson AD, Maini MK, McKeating JA. Wing PAC, et al. Among authors: shionoya k. PLoS Pathog. 2023 May 3;19(5):e1011323. doi: 10.1371/journal.ppat.1011323. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37134108 Free PMC article.
Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents.
Hishiki T, Morita T, Akazawa D, Ohashi H, Park ES, Kataoka M, Mifune J, Shionoya K, Tsuchimoto K, Ojima S, Azam AH, Nakajima S, Kawahara M, Yoshikawa T, Shimojima M, Kiga K, Maeda K, Suzuki T, Ebihara H, Takahashi Y, Watashi K. Hishiki T, et al. Among authors: shionoya k. Microbiol Spectr. 2023 Aug 17;11(4):e0056623. doi: 10.1128/spectrum.00566-23. Epub 2023 Jul 6. Microbiol Spectr. 2023. PMID: 37409948 Free PMC article.
88 results