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Fluorescent retinoid X receptor ligands for fluorescence polarization assay.
Yamada S, Ohsawa F, Fujii S, Shinozaki R, Makishima M, Naitou H, Enomoto S, Tai A, Kakuta H. Yamada S, et al. Among authors: shinozaki r. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5143-6. doi: 10.1016/j.bmcl.2010.07.011. Epub 2010 Jul 8. Bioorg Med Chem Lett. 2010. PMID: 20667726
Mechanism of retinoid X receptor partial agonistic action of 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid and structural development to increase potency.
Ohsawa F, Yamada S, Yakushiji N, Shinozaki R, Nakayama M, Kawata K, Hagaya M, Kobayashi T, Kohara K, Furusawa Y, Fujiwara C, Ohta Y, Makishima M, Naitou H, Tai A, Yoshikawa Y, Yasui H, Kakuta H. Ohsawa F, et al. Among authors: shinozaki r. J Med Chem. 2013 Mar 14;56(5):1865-77. doi: 10.1021/jm400033f. Epub 2013 Feb 20. J Med Chem. 2013. PMID: 23391145
RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists.
Kakuta H, Yakushiji N, Shinozaki R, Ohsawa F, Yamada S, Ohta Y, Kawata K, Nakayama M, Hagaya M, Fujiwara C, Makishima M, Uno S, Tai A, Maehara A, Nakayama M, Oohashi T, Yasui H, Yoshikawa Y. Kakuta H, et al. Among authors: shinozaki r. ACS Med Chem Lett. 2012 Apr 9;3(5):427-32. doi: 10.1021/ml300055n. eCollection 2012 May 10. ACS Med Chem Lett. 2012. PMID: 24900488 Free PMC article.
Aberrant DNA methylation-mediated NF-κB/fatty acid-binding protein 5 (FABP5) feed-forward loop promotes malignancy of colorectal cancer cells.
Kawaguchi K, Ohashi T, Kobayashi N, Kanemoto K, Nose M, Shinozaki R, Kataoka T, Fujii H. Kawaguchi K, et al. Among authors: shinozaki r. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Sep;1868(9):159362. doi: 10.1016/j.bbalip.2023.159362. Epub 2023 Jul 4. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 37414211
Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota.
Chen X, Hashimoto D, Ebata K, Takahashi S, Shimizu Y, Shinozaki R, Hasegawa Y, Kikuchi R, Senjo H, Yoneda K, Zhang Z, Harada S, Hayase E, Ara T, Ohigashi H, Iwakura Y, Nakamura K, Ayabe T, Teshima T. Chen X, et al. Among authors: shinozaki r. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2211230119. doi: 10.1073/pnas.2211230119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409919 Free PMC article.
42 results