Shin SY - Search Results

1

The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer.

Yang X, Cruz MI, Nguyen EV, Huang C, Schittenhelm RB, Luu J, Cowley KJ, Shin SY, Nguyen LK, Lim Kam Sian TCC, Clark KC, Simpson KJ, Ma X, Daly RJ. Yang X, et al. Among authors: shin sy. Oncogene. 2023 Mar;42(11):833-847. doi: 10.1038/s41388-023-02594-w. Epub 2023 Jan 24. Oncogene. 2023. PMID: 36693952 Free PMC article.

2

Unveiling Hidden Dynamics of Hippo Signalling: A Systems Analysis.

Shin SY, Nguyen LK. Shin SY, et al. Genes (Basel). 2016 Aug 5;7(8):44. doi: 10.3390/genes7080044. Genes (Basel). 2016. PMID: 27527217 Free PMC article.

3

Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis.

Verma N, Müller AK, Kothari C, Panayotopoulou E, Kedan A, Selitrennik M, Mills GB, Nguyen LK, Shin S, Karn T, Holtrich U, Lev S. Verma N, et al. Cancer Res. 2017 Jan 1;77(1):86-99. doi: 10.1158/0008-5472.CAN-16-1797. Epub 2016 Oct 28. Cancer Res. 2017. PMID: 27793840

4

Dissecting Cell-Fate Determination Through Integrated Mathematical Modeling of the ERK/MAPK Signaling Pathway.

Shin SY, Nguyen LK. Shin SY, et al. Methods Mol Biol. 2017;1487:409-432. doi: 10.1007/978-1-4939-6424-6_29. Methods Mol Biol. 2017. PMID: 27924583 Review.

5

Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer.

Shin SY, Müller AK, Verma N, Lev S, Nguyen LK. Shin SY, et al. PLoS Comput Biol. 2018 Jun 19;14(6):e1006192. doi: 10.1371/journal.pcbi.1006192. eCollection 2018 Jun. PLoS Comput Biol. 2018. PMID: 29920512 Free PMC article.

6

Coupled feedback regulation of nuclear factor of activated T-cells (NFAT) modulates activation-induced cell death of T cells.

Shin SY, Kim MW, Cho KH, Nguyen LK. Shin SY, et al. Sci Rep. 2019 Jul 23;9(1):10637. doi: 10.1038/s41598-019-46592-z. Sci Rep. 2019. PMID: 31337782 Free PMC article.

7

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt.

Su Z, Burchfield JG, Yang P, Humphrey SJ, Yang G, Francis D, Yasmin S, Shin SY, Norris DM, Kearney AL, Astore MA, Scavuzzo J, Fisher-Wellman KH, Wang QP, Parker BL, Neely GG, Vafaee F, Chiu J, Yeo R, Hogg PJ, Fazakerley DJ, Nguyen LK, Kuyucak S, James DE. Su Z, et al. Among authors: shin sy. Nat Commun. 2019 Dec 2;10(1):5486. doi: 10.1038/s41467-019-13114-4. Nat Commun. 2019. PMID: 31792197 Free PMC article.

8

Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression.

Yip HYK, Chee A, Ang CS, Shin SY, Ooms LM, Mohammadi Z, Phillips WA, Daly RJ, Cole TJ, Bronson RT, Nguyen LK, Tiganis T, Hobbs RM, McLean CA, Mitchell CA, Papa A. Yip HYK, et al. Among authors: shin sy. Mol Cell. 2020 Oct 15;80(2):279-295.e8. doi: 10.1016/j.molcel.2020.09.027. Mol Cell. 2020. PMID: 33065020 Free article.

9

Signaling Heterogeneity is Defined by Pathway Architecture and Intercellular Variability in Protein Expression.

Norris D, Yang P, Shin SY, Kearney AL, Kim HJ, Geddes T, Senior AM, Fazakerley DJ, Nguyen LK, James DE, Burchfield JG. Norris D, et al. Among authors: shin sy. iScience. 2021 Jan 29;24(2):102118. doi: 10.1016/j.isci.2021.102118. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659881 Free PMC article.

10

Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network.

Ghomlaghi M, Hart A, Hoang N, Shin S, Nguyen LK. Ghomlaghi M, et al. Int J Mol Sci. 2021 Jun 28;22(13):6944. doi: 10.3390/ijms22136944. Int J Mol Sci. 2021. PMID: 34203293 Free PMC article. Review.

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