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Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53.
Jing K, Song KS, Shin S, Kim N, Jeong S, Oh HR, Park JH, Seo KS, Heo JY, Han J, Park JI, Han C, Wu T, Kweon GR, Park SK, Yoon WH, Hwang BD, Lim K. Jing K, et al. Among authors: shin s. Autophagy. 2011 Nov;7(11):1348-58. doi: 10.4161/auto.7.11.16658. Epub 2011 Nov 1. Autophagy. 2011. PMID: 21811093 Free PMC article.
The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53.
Shin S, Jing K, Jeong S, Kim N, Song KS, Heo JY, Park JH, Seo KS, Han J, Park JI, Kweon GR, Park SK, Wu T, Hwang BD, Lim K. Shin S, et al. Biomed Res Int. 2013;2013:568671. doi: 10.1155/2013/568671. Epub 2013 Jun 10. Biomed Res Int. 2013. PMID: 23841076 Free PMC article.
Crif1 deficiency in dopamine neurons triggers early-onset parkinsonism.
Heo JY, Park AH, Lee MJ, Ryu MJ, Kim YK, Jang YS, Kim SJ, Shin SY, Son HJ, Stein TD, Huh YH, Chung SK, Choi SY, Kim JM, Hwang O, Shong M, Hyeon SJ, Lee J, Ryu H, Kim D, Kweon GR. Heo JY, et al. Mol Psychiatry. 2023 Oct;28(10):4474-4484. doi: 10.1038/s41380-023-02234-5. Epub 2023 Aug 30. Mol Psychiatry. 2023. PMID: 37648779
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