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Disabling Cas9 by an anti-CRISPR DNA mimic.
Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA. Shin J, et al. Sci Adv. 2017 Jul 12;3(7):e1701620. doi: 10.1126/sciadv.1701620. eCollection 2017 Jul. Sci Adv. 2017. PMID: 28706995 Free PMC article.
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair.
Wienert B, Nguyen DN, Guenther A, Feng SJ, Locke MN, Wyman SK, Shin J, Kazane KR, Gregory GL, Carter MAM, Wright F, Conklin BR, Marson A, Richardson CD, Corn JE. Wienert B, et al. Nat Commun. 2020 Apr 30;11(1):2109. doi: 10.1038/s41467-020-15845-1. Nat Commun. 2020. PMID: 32355159 Free PMC article.
SIRT3 reverses aging-associated degeneration.
Brown K, Xie S, Qiu X, Mohrin M, Shin J, Liu Y, Zhang D, Scadden DT, Chen D. Brown K, et al. Cell Rep. 2013 Feb 21;3(2):319-27. doi: 10.1016/j.celrep.2013.01.005. Epub 2013 Jan 31. Cell Rep. 2013. PMID: 23375372 Free PMC article.
SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.
Shin J, He M, Liu Y, Paredes S, Villanova L, Brown K, Qiu X, Nabavi N, Mohrin M, Wojnoonski K, Li P, Cheng HL, Murphy AJ, Valenzuela DM, Luo H, Kapahi P, Krauss R, Mostoslavsky R, Yancopoulos GD, Alt FW, Chua KF, Chen D. Shin J, et al. Cell Rep. 2013 Nov 14;5(3):654-665. doi: 10.1016/j.celrep.2013.10.007. Epub 2013 Nov 7. Cell Rep. 2013. PMID: 24210820 Free PMC article.
345 results