Shin HC - Search Results

1

Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin HC, Lennernas H, Zhong Y, Amidon GL, Yu LX, Sun D. Cao X, et al. Among authors: shin hc. Pharm Res. 2006 Aug;23(8):1675-86. doi: 10.1007/s11095-006-9041-2. Pharm Res. 2006. PMID: 16841194 Review.

2

Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability.

Cao X, Yu LX, Barbaciru C, Landowski CP, Shin HC, Gibbs S, Miller HA, Amidon GL, Sun D. Cao X, et al. Among authors: shin hc. Mol Pharm. 2005 Jul-Aug;2(4):329-40. doi: 10.1021/mp0499104. Mol Pharm. 2005. PMID: 16053336

3

Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis.

Vig BS, Lorenzi PJ, Mittal S, Landowski CP, Shin HC, Mosberg HI, Hilfinger JM, Amidon GL. Vig BS, et al. Among authors: shin hc. Pharm Res. 2003 Sep;20(9):1381-8. doi: 10.1023/a:1025745824632. Pharm Res. 2003. PMID: 14567631 Free article.

4

Comparative gene expression profiles of intestinal transporters in mice, rats and humans.

Kim HR, Park SW, Cho HJ, Chae KA, Sung JM, Kim JS, Landowski CP, Sun D, Abd El-Aty AM, Amidon GL, Shin HC. Kim HR, et al. Among authors: shin hc. Pharmacol Res. 2007 Sep;56(3):224-36. doi: 10.1016/j.phrs.2007.06.005. Epub 2007 Jun 23. Pharmacol Res. 2007. PMID: 17681807

5

Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.

Shin HC, Landowski CP, Sun D, Vig BS, Kim I, Mittal S, Lane M, Rosania G, Drach JC, Amidon GL. Shin HC, et al. Biochem Biophys Res Commun. 2003 Aug 1;307(3):696-703. doi: 10.1016/s0006-291x(03)01259-2. Biochem Biophys Res Commun. 2003. PMID: 12893280

6

Interaction of intestinal nucleoside transporter hCNT2 with amino acid ester prodrugs of floxuridine and 2-bromo-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.

Shin HC, Kim JS, Vig BS, Song X, Drach JC, Amidon GL. Shin HC, et al. Biol Pharm Bull. 2006 Feb;29(2):247-52. doi: 10.1248/bpb.29.247. Biol Pharm Bull. 2006. PMID: 16462026 Free article.

7

Comparative gene expression of intestinal metabolizing enzymes.

Shin HC, Kim HR, Cho HJ, Yi H, Cho SM, Lee DG, Abd El-Aty AM, Kim JS, Sun D, Amidon GL. Shin HC, et al. Biopharm Drug Dispos. 2009 Nov;30(8):411-21. doi: 10.1002/bdd.675. Biopharm Drug Dispos. 2009. PMID: 19746353 Free article. Clinical Trial.

8

Fetal and maternal tissue distribution of the new fluoroquinolone DW-116 in pregnant rats.

Shin HC, Kim JC, Chung MK, Jung YH, Kim JS, Lee MK, Amidon GL. Shin HC, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Sep;136(1):95-102. doi: 10.1016/j.cca.2003.08.004. Comp Biochem Physiol C Toxicol Pharmacol. 2003. PMID: 14522602

9

A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein.

Kim I, Song X, Vig BS, Mittal S, Shin HC, Lorenzi PJ, Amidon GL. Kim I, et al. Among authors: shin hc. Mol Pharm. 2004 Mar-Apr;1(2):117-27. doi: 10.1021/mp0499757. Mol Pharm. 2004. PMID: 15832508

10

Characterization of a stem cell population in lung cancer A549 cells.

Sung JM, Cho HJ, Yi H, Lee CH, Kim HS, Kim DK, Abd El-Aty AM, Kim JS, Landowski CP, Hediger MA, Shin HC. Sung JM, et al. Among authors: shin hc. Biochem Biophys Res Commun. 2008 Jun 20;371(1):163-7. doi: 10.1016/j.bbrc.2008.04.038. Epub 2008 Apr 24. Biochem Biophys Res Commun. 2008. PMID: 18423378

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