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Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis.
Kim S, Leem G, Choi J, Koh Y, Lee S, Nam SH, Kim JS, Park CH, Hwang HK, Min KI, Jo JH, Lee HS, Chung MJ, Park JY, Park SW, Song SY, Shin EC, Kang CM, Bang S, Park JE. Kim S, et al. Among authors: shin ec. Genome Med. 2024 Jan 31;16(1):20. doi: 10.1186/s13073-024-01287-7. Genome Med. 2024. PMID: 38297291 Free PMC article.
VEGF-A drives TOX-dependent T cell exhaustion in anti-PD-1-resistant microsatellite stable colorectal cancers.
Kim CG, Jang M, Kim Y, Leem G, Kim KH, Lee H, Kim TS, Choi SJ, Kim HD, Han JW, Kwon M, Kim JH, Lee AJ, Nam SK, Bae SJ, Lee SB, Shin SJ, Park SH, Ahn JB, Jung I, Lee KY, Park SH, Kim H, Min BS, Shin EC. Kim CG, et al. Among authors: shin sj, shin ec. Sci Immunol. 2019 Nov 8;4(41):eaay0555. doi: 10.1126/sciimmunol.aay0555. Sci Immunol. 2019. PMID: 31704735
4-1BB co-stimulation further enhances anti-PD-1-mediated reinvigoration of exhausted CD39+ CD8 T cells from primary and metastatic sites of epithelial ovarian cancers.
Leem G, Park J, Jeon M, Kim ES, Kim SW, Lee YJ, Choi SJ, Choi B, Park S, Ju YS, Jung I, Kim S, Shin EC, Lee JY, Park SH. Leem G, et al. Among authors: shin ec. J Immunother Cancer. 2020 Dec;8(2):e001650. doi: 10.1136/jitc-2020-001650. J Immunother Cancer. 2020. PMID: 33335029 Free PMC article.
Abnormality in the NK-cell population is prolonged in severe COVID-19 patients.
Leem G, Cheon S, Lee H, Choi SJ, Jeong S, Kim ES, Jeong HW, Jeong H, Park SH, Kim YS, Shin EC. Leem G, et al. Among authors: shin ec. J Allergy Clin Immunol. 2021 Oct;148(4):996-1006.e18. doi: 10.1016/j.jaci.2021.07.022. Epub 2021 Jul 31. J Allergy Clin Immunol. 2021. PMID: 34339730 Free PMC article.
Tumor-Infiltrating Regulatory T-cell Accumulation in the Tumor Microenvironment Is Mediated by IL33/ST2 Signaling.
Son J, Cho JW, Park HJ, Moon J, Park S, Lee H, Lee J, Kim G, Park SM, Lira SA, Mckenzie AN, Kim HY, Choi CY, Lim YT, Park SY, Kim HR, Park SH, Shin EC, Lee I, Ha SJ. Son J, et al. Among authors: shin ec. Cancer Immunol Res. 2020 Nov;8(11):1393-1406. doi: 10.1158/2326-6066.CIR-19-0828. Epub 2020 Sep 2. Cancer Immunol Res. 2020. PMID: 32878747
Dynamic changes in circulating PD-1+CD8+ T lymphocytes for predicting treatment response to PD-1 blockade in patients with non-small-cell lung cancer.
Kim CG, Hong MH, Kim KH, Seo IH, Ahn BC, Pyo KH, Synn CB, Yoon HI, Shim HS, Lee YI, Choi SJ, Lee YJ, Kim EJ, Kim Y, Kwak JE, Jung J, Park SH, Paik S, Shin EC, Kim HR. Kim CG, et al. Among authors: shin ec. Eur J Cancer. 2021 Jan;143:113-126. doi: 10.1016/j.ejca.2020.10.028. Epub 2020 Dec 7. Eur J Cancer. 2021. PMID: 33302114
Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values.
Kim AR, Choi KS, Kim MS, Kim KM, Kang H, Kim S, Chowdhury T, Yu HJ, Lee CE, Lee JH, Lee ST, Won JK, Kim JW, Kim YH, Kim TM, Park SH, Choi SH, Shin EC, Park CK. Kim AR, et al. Among authors: shin ec. Cancer Immunol Immunother. 2021 Jul;70(7):1995-2008. doi: 10.1007/s00262-020-02836-w. Epub 2021 Jan 8. Cancer Immunol Immunother. 2021. PMID: 33416947 Free PMC article.
368 results