Shimohata A - Search Results

1

Impaired cortico-striatal excitatory transmission triggers epilepsy.

Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K. Miyamoto H, et al. Among authors: shimohata a. Nat Commun. 2019 Apr 23;10(1):1917. doi: 10.1038/s41467-019-09954-9. Nat Commun. 2019. PMID: 31015467 Free PMC article.

2

Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.

Shukkur EA, Shimohata A, Akagi T, Yu W, Yamaguchi M, Murayama M, Chui D, Takeuchi T, Amano K, Subramhanya KH, Hashikawa T, Sago H, Epstein CJ, Takashima A, Yamakawa K. Shukkur EA, et al. Among authors: shimohata a. Hum Mol Genet. 2006 Sep 15;15(18):2752-62. doi: 10.1093/hmg/ddl211. Epub 2006 Aug 4. Hum Mol Genet. 2006. PMID: 16891409

3

DSCAM deficiency causes loss of pre-inspiratory neuron synchroneity and perinatal death.

Amano K, Fujii M, Arata S, Tojima T, Ogawa M, Morita N, Shimohata A, Furuichi T, Itohara S, Kamiguchi H, Korenberg JR, Arata A, Yamakawa K. Amano K, et al. Among authors: shimohata a. J Neurosci. 2009 Mar 4;29(9):2984-96. doi: 10.1523/JNEUROSCI.3624-08.2009. J Neurosci. 2009. PMID: 19261893 Free PMC article.

4

Increased lipid peroxidation in Down's syndrome mouse models.

Ishihara K, Amano K, Takaki E, Ebrahim AS, Shimohata A, Shibazaki N, Inoue I, Takaki M, Ueda Y, Sago H, Epstein CJ, Yamakawa K. Ishihara K, et al. Among authors: shimohata a. J Neurochem. 2009 Sep;110(6):1965-76. doi: 10.1111/j.1471-4159.2009.06294.x. Epub 2009 Jul 23. J Neurochem. 2009. PMID: 19645748 Free article.

5

Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of Down syndrome.

Ishihara K, Amano K, Takaki E, Shimohata A, Sago H, Epstein CJ, Yamakawa K. Ishihara K, et al. Among authors: shimohata a. Cereb Cortex. 2010 May;20(5):1131-43. doi: 10.1093/cercor/bhp176. Epub 2009 Aug 26. Cereb Cortex. 2010. PMID: 19710359

6

Brain ventriculomegaly in Down syndrome mice is caused by Pcp4 dose-dependent cilia dysfunction.

Raveau M, Nakahari T, Asada S, Ishihara K, Amano K, Shimohata A, Sago H, Yamakawa K. Raveau M, et al. Among authors: shimohata a. Hum Mol Genet. 2017 Mar 1;26(5):923-931. doi: 10.1093/hmg/ddx007. Hum Mol Genet. 2017. PMID: 28069794

7

Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.

Shimohata A, Ishihara K, Hattori S, Miyamoto H, Morishita H, Ornthanalai G, Raveau M, Ebrahim AS, Amano K, Yamada K, Sago H, Akiba S, Mataga N, Murphy NP, Miyakawa T, Yamakawa K. Shimohata A, et al. Exp Neurol. 2017 Jul;293:1-12. doi: 10.1016/j.expneurol.2017.03.009. Epub 2017 Mar 20. Exp Neurol. 2017. PMID: 28336394

8

Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency.

Miyamoto H, Shimohata A, Abe M, Abe T, Mazaki E, Amano K, Suzuki T, Tatsukawa T, Itohara S, Sakimura K, Yamakawa K. Miyamoto H, et al. Among authors: shimohata a. Hum Mol Genet. 2017 Dec 15;26(24):4961-4974. doi: 10.1093/hmg/ddx379. Hum Mol Genet. 2017. PMID: 29040524

9

DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures.

Raveau M, Shimohata A, Amano K, Miyamoto H, Yamakawa K. Raveau M, et al. Among authors: shimohata a. Neurobiol Dis. 2018 Feb;110:180-191. doi: 10.1016/j.nbd.2017.12.003. Epub 2017 Dec 6. Neurobiol Dis. 2018. PMID: 29223763

10

Impairments in social novelty recognition and spatial memory in mice with conditional deletion of Scn1a in parvalbumin-expressing cells.

Tatsukawa T, Ogiwara I, Mazaki E, Shimohata A, Yamakawa K. Tatsukawa T, et al. Among authors: shimohata a. Neurobiol Dis. 2018 Apr;112:24-34. doi: 10.1016/j.nbd.2018.01.009. Epub 2018 Jan 11. Neurobiol Dis. 2018. PMID: 29337050

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