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Early administration of galantamine from preplaque phase suppresses oxidative stress and improves cognitive behavior in APPswe/PS1dE9 mouse model of Alzheimer's disease.
Saito T, Hisahara S, Iwahara N, Emoto MC, Yokokawa K, Suzuki H, Manabe T, Matsumura A, Suzuki S, Matsushita T, Kawamata J, Sato-Akaba H, Fujii HG, Shimohama S. Saito T, et al. Among authors: shimohama s. Free Radic Biol Med. 2019 Dec;145:20-32. doi: 10.1016/j.freeradbiomed.2019.09.014. Epub 2019 Sep 16. Free Radic Biol Med. 2019. PMID: 31536772
Stimulation of nicotinic acetylcholine receptors protects motor neurons.
Nakamizo T, Kawamata J, Yamashita H, Kanki R, Kihara T, Sawada H, Akaike A, Shimohama S. Nakamizo T, et al. Among authors: shimohama s. Biochem Biophys Res Commun. 2005 May 20;330(4):1285-9. doi: 10.1016/j.bbrc.2005.03.115. Biochem Biophys Res Commun. 2005. PMID: 15823582
Protein trafficking and Alzheimer's disease.
Uemura K, Kuzuya A, Shimohama S. Uemura K, et al. Among authors: shimohama s. Curr Alzheimer Res. 2004 Feb;1(1):1-10. doi: 10.2174/1567205043480528. Curr Alzheimer Res. 2004. PMID: 15975080 Review.
N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein: implications for neurodegeneration in Alzheimer disease.
Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A. Ando K, et al. Among authors: shimohama s. J Biol Chem. 2011 Mar 4;286(9):7619-28. doi: 10.1074/jbc.M110.158477. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177868 Free PMC article.
390 results