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Disease model: Parkinson's disease.
Shimohama S, Sawada H, Kitamura Y, Taniguchi T. Shimohama S, et al. Trends Mol Med. 2003 Aug;9(8):360-5. doi: 10.1016/s1471-4914(03)00117-5. Trends Mol Med. 2003. PMID: 12928038 Review.
Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions.
Sawada H, Kohno R, Kihara T, Izumi Y, Sakka N, Ibi M, Nakanishi M, Nakamizo T, Yamakawa K, Shibasaki H, Yamamoto N, Akaike A, Inden M, Kitamura Y, Taniguchi T, Shimohama S. Sawada H, et al. Among authors: shimohama s. J Biol Chem. 2004 Mar 12;279(11):10710-9. doi: 10.1074/jbc.M308434200. Epub 2003 Dec 12. J Biol Chem. 2004. PMID: 14672949 Free article.
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model.
Inden M, Taira T, Kitamura Y, Yanagida T, Tsuchiya D, Takata K, Yanagisawa D, Nishimura K, Taniguchi T, Kiso Y, Yoshimoto K, Agatsuma T, Koide-Yoshida S, Iguchi-Ariga SM, Shimohama S, Ariga H. Inden M, et al. Among authors: shimohama s. Neurobiol Dis. 2006 Oct;24(1):144-58. doi: 10.1016/j.nbd.2006.06.004. Epub 2006 Jul 24. Neurobiol Dis. 2006. PMID: 16860563
390 results