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R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm.
Shide K, Kameda T, Markovtsov V, Shimoda HK, Tonkin E, Fang S, Liu C, Gelman M, Lang W, Romero J, McLaughlin J, Bhamidipati S, Clough J, Low C, Reitsma A, Siu S, Pine P, Park G, Torneros A, Duan M, Singh R, Payan DG, Matsunaga T, Hitoshi Y, Shimoda K. Shide K, et al. Among authors: shimoda hk, shimoda k. Blood. 2011 Jun 23;117(25):6866-75. doi: 10.1182/blood-2010-01-262535. Epub 2011 Apr 29. Blood. 2011. PMID: 21531978 Free article.
Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F.
Shide K, Shimoda HK, Kumano T, Karube K, Kameda T, Takenaka K, Oku S, Abe H, Katayose KS, Kubuki Y, Kusumoto K, Hasuike S, Tahara Y, Nagata K, Matsuda T, Ohshima K, Harada M, Shimoda K. Shide K, et al. Among authors: shimoda hk, shimoda k. Leukemia. 2008 Jan;22(1):87-95. doi: 10.1038/sj.leu.2405043. Epub 2007 Nov 22. Leukemia. 2008. PMID: 18033315
p27 deregulation by Skp2 overexpression induced by the JAK2V617 mutation.
Furuhata A, Kimura A, Shide K, Shimoda K, Murakami M, Ito H, Gao S, Yoshida K, Tagawa Y, Hagiwara K, Takagi A, Kojima T, Suzuki M, Abe A, Naoe T, Murate T. Furuhata A, et al. Among authors: shimoda k. Biochem Biophys Res Commun. 2009 Jun 12;383(4):411-6. doi: 10.1016/j.bbrc.2009.04.015. Epub 2009 Apr 11. Biochem Biophys Res Commun. 2009. PMID: 19364496
The impact of cytogenetic abnormalities on the prognosis of primary myelofibrosis: a prospective survey of 202 cases in Japan.
Hidaka T, Shide K, Shimoda H, Kameda T, Toyama K, Katayose K, Kubuki Y, Nagata K, Takenaka K, Akashi K, Okamura T, Niho Y, Mizoguchi H, Omine M, Ozawa K, Harada M, Shimoda K. Hidaka T, et al. Among authors: shimoda h, shimoda k. Eur J Haematol. 2009 Oct;83(4):328-33. doi: 10.1111/j.1600-0609.2009.01298.x. Epub 2009 Jun 15. Eur J Haematol. 2009. PMID: 19549278
862 results