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p63 is a cereblon substrate involved in thalidomide teratogenicity.
Asatsuma-Okumura T, Ando H, De Simone M, Yamamoto J, Sato T, Shimizu N, Asakawa K, Yamaguchi Y, Ito T, Guerrini L, Handa H. Asatsuma-Okumura T, et al. Among authors: shimizu n. Nat Chem Biol. 2019 Nov;15(11):1077-1084. doi: 10.1038/s41589-019-0366-7. Epub 2019 Oct 7. Nat Chem Biol. 2019. PMID: 31591562
ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells.
Yamamoto J, Suwa T, Murase Y, Tateno S, Mizutome H, Asatsuma-Okumura T, Shimizu N, Kishi T, Momose S, Kizaki M, Ito T, Yamaguchi Y, Handa H. Yamamoto J, et al. Among authors: shimizu n. Nat Chem Biol. 2020 Nov;16(11):1208-1217. doi: 10.1038/s41589-020-0645-3. Epub 2020 Sep 21. Nat Chem Biol. 2020. PMID: 32958952
Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1.
Apridita Sebastian W, Shiraishi H, Shimizu N, Umeda R, Lai S, Ikeuchi M, Morisaki I, Yano S, Yoshimura A, Hanada R, Hanada T. Apridita Sebastian W, et al. Among authors: shimizu n. Biochem Biophys Res Commun. 2022 Oct 8;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Epub 2022 Jul 31. Biochem Biophys Res Commun. 2022. PMID: 35940133
Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model.
Sebastian WA, Inoue M, Shimizu N, Sato R, Oguri S, Itonaga T, Kishimoto S, Shiraishi H, Hanada T, Ihara K. Sebastian WA, et al. Among authors: shimizu n. J Hum Genet. 2024 Apr;69(3-4):133-138. doi: 10.1038/s10038-024-01221-0. Epub 2024 Feb 5. J Hum Genet. 2024. PMID: 38316882 Free PMC article.
Vrk2 deficiency elicits aggressive behavior in female zebrafish.
Umeda R, Teranishi H, Hada K, Shimizu N, Shiraishi H, Urushibata H, Lai S, Shide M, Carrasco Apolinario ME, Higa R, Shikano K, Shin T, Mimata H, Hikida T, Hanada T, Hanada R. Umeda R, et al. Among authors: shimizu n. Genes Cells. 2022 Apr;27(4):254-265. doi: 10.1111/gtc.12924. Epub 2022 Feb 15. Genes Cells. 2022. PMID: 35094457 Free article.
3,197 results