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Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Yoshida Y, Shimizu I, Shimada A, Nakahara K, Yanagisawa S, Kubo M, Fukuda S, Ishii C, Yamamoto H, Ishikawa T, Kano K, Aoki J, Katsuumi G, Suda M, Ozaki K, Yoshida Y, Okuda S, Ohta S, Okamoto S, Minokoshi Y, Oda K, Sasaoka T, Abe M, Sakimura K, Kubota Y, Yoshimura N, Kajimura S, Zuriaga M, Walsh K, Soga T, Minamino T. Yoshida Y, et al. Among authors: shimizu i. Sci Rep. 2022 Sep 1;12(1):14883. doi: 10.1038/s41598-022-19245-x. Sci Rep. 2022. PMID: 36050466 Free PMC article.
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.
Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I. Sano M, et al. Among authors: shimizu i. Nature. 2007 Mar 22;446(7134):444-8. doi: 10.1038/nature05602. Epub 2007 Mar 4. Nature. 2007. PMID: 17334357
Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure.
Kayama Y, Minamino T, Toko H, Sakamoto M, Shimizu I, Takahashi H, Okada S, Tateno K, Moriya J, Yokoyama M, Nojima A, Yoshimura M, Egashira K, Aburatani H, Komuro I. Kayama Y, et al. Among authors: shimizu i. J Exp Med. 2009 Jul 6;206(7):1565-74. doi: 10.1084/jem.20082596. Epub 2009 Jun 22. J Exp Med. 2009. PMID: 19546247 Free PMC article.
Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice.
Yasuda N, Akazawa H, Ito K, Shimizu I, Kudo-Sakamoto Y, Yabumoto C, Yano M, Yamamoto R, Ozasa Y, Minamino T, Naito AT, Oka T, Shiojima I, Tamura K, Umemura S, Paradis P, Nemer M, Komuro I. Yasuda N, et al. Among authors: shimizu i. Hypertension. 2012 Mar;59(3):627-33. doi: 10.1161/HYPERTENSIONAHA.111.175208. Epub 2012 Jan 30. Hypertension. 2012. PMID: 22291447
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway.
Okada S, Yokoyama M, Toko H, Tateno K, Moriya J, Shimizu I, Nojima A, Ito T, Yoshida Y, Kobayashi Y, Katagiri H, Minamino T, Komuro I. Okada S, et al. Among authors: shimizu i. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1902-9. doi: 10.1161/ATVBAHA.112.248930. Epub 2012 May 3. Arterioscler Thromb Vasc Biol. 2012. PMID: 22556331
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.
Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I. Naito AT, et al. Among authors: shimizu i. Cell. 2012 Jun 8;149(6):1298-313. doi: 10.1016/j.cell.2012.03.047. Cell. 2012. PMID: 22682250 Free PMC article.
Adipose tissue inflammation in diabetes and heart failure.
Shimizu I, Yoshida Y, Katsuno T, Minamino T. Shimizu I, et al. Microbes Infect. 2013 Jan;15(1):11-7. doi: 10.1016/j.micinf.2012.10.012. Epub 2012 Oct 29. Microbes Infect. 2013. PMID: 23116945 Free article. Review.
520 results