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Discovery of Novel Pyrazole-Based Selective Aldosterone Synthase (CYP11B2) Inhibitors: A New Template to Coordinate the Heme-Iron Motif of CYP11B2.
Sakakibara R, Sasaki W, Onda Y, Yamaguchi M, Ushirogochi H, Hiraga Y, Sato K, Nishio M, Egi Y, Takedomi K, Shimizu H, Ohbora T, Akahoshi F. Sakakibara R, et al. Among authors: shimizu h. J Med Chem. 2018 Jul 12;61(13):5594-5608. doi: 10.1021/acs.jmedchem.8b00328. Epub 2018 Jun 22. J Med Chem. 2018. PMID: 29878770
A Randomized, Single-Blind, Placebo-Controlled, 3-Way Crossover Study to Evaluate the Effect of Therapeutic and Supratherapeutic Doses of Edaravone on QT/QTc Interval in Healthy Subjects.
Shimizu H, Inoue S, Endo M, Nakamaru Y, Yoshida K, Natori T, Kakubari M, Akimoto M, Kondo K. Shimizu H, et al. Clin Pharmacol Drug Dev. 2021 Jan;10(1):46-56. doi: 10.1002/cpdd.814. Epub 2020 Jun 15. Clin Pharmacol Drug Dev. 2021. PMID: 32543120 Free PMC article. Clinical Trial.
Publisher Correction: Evaluation of Age-Related Changes in Teneligliptin Pharmacokinetics in Japanese and European Descent Subjects Using a Physiologically Based Pharmacokinetic Model.
Iijima H, Shimizu H, Mori-Anai K, Kawaguchi A, Mochida Y, Yamauchi T, Kadowaki T. Iijima H, et al. Among authors: shimizu h. Diabetes Ther. 2024 Apr;15(4):779-780. doi: 10.1007/s13300-024-01548-z. Diabetes Ther. 2024. PMID: 38421560 Free PMC article. No abstract available.
6,227 results