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434 results

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Page 1
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. Yahagi N, et al. Among authors: shimano h. J Biol Chem. 2002 May 31;277(22):19353-7. doi: 10.1074/jbc.M201584200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923308 Free article.
p53 Activation in adipocytes of obese mice.
Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Gotoda T, Nagai R, Kimura S, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: shimano h. J Biol Chem. 2003 Jul 11;278(28):25395-400. doi: 10.1074/jbc.M302364200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734185 Free article.
SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.
Yamamoto T, Shimano H, Nakagawa Y, Ide T, Yahagi N, Matsuzaka T, Nakakuki M, Takahashi A, Suzuki H, Sone H, Toyoshima H, Sato R, Yamada N. Yamamoto T, et al. Among authors: shimano h. J Biol Chem. 2004 Mar 26;279(13):12027-35. doi: 10.1074/jbc.M310333200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722127 Free article.
p53 involvement in the pathogenesis of fatty liver disease.
Yahagi N, Shimano H, Matsuzaka T, Sekiya M, Najima Y, Okazaki S, Okazaki H, Tamura Y, Iizuka Y, Inoue N, Nakagawa Y, Takeuchi Y, Ohashi K, Harada K, Gotoda T, Nagai R, Kadowaki T, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: shimano h. J Biol Chem. 2004 May 14;279(20):20571-5. doi: 10.1074/jbc.M400884200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985341 Free article.
Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice.
Matsuzaka T, Shimano H, Yahagi N, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Tomita S, Sekiya M, Hasty A, Nakagawa Y, Sone H, Toyoshima H, Ishibashi S, Osuga J, Yamada N. Matsuzaka T, et al. Among authors: shimano h. Diabetes. 2004 Mar;53(3):560-9. doi: 10.2337/diabetes.53.3.560. Diabetes. 2004. PMID: 14988238
Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages.
Sone H, Shimano H, Shu M, Nakakuki M, Takahashi A, Sakai M, Sakamoto Y, Yokoo T, Matsuzaka K, Okazaki H, Nakagawa Y, Iida KT, Suzuki H, Toyoshima H, Horiuchi S, Yamada N. Sone H, et al. Among authors: shimano h. Biochem Biophys Res Commun. 2004 Apr 9;316(3):790-4. doi: 10.1016/j.bbrc.2004.02.121. Biochem Biophys Res Commun. 2004. PMID: 15033469
SREBPs suppress IRS-2-mediated insulin signalling in the liver.
Ide T, Shimano H, Yahagi N, Matsuzaka T, Nakakuki M, Yamamoto T, Nakagawa Y, Takahashi A, Suzuki H, Sone H, Toyoshima H, Fukamizu A, Yamada N. Ide T, et al. Among authors: shimano h. Nat Cell Biol. 2004 Apr;6(4):351-7. doi: 10.1038/ncb1111. Epub 2004 Mar 14. Nat Cell Biol. 2004. PMID: 15048126
Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells.
Takahashi A, Motomura K, Kato T, Yoshikawa T, Nakagawa Y, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N, Shimano H. Takahashi A, et al. Among authors: shimano h. Diabetes. 2005 Feb;54(2):492-9. doi: 10.2337/diabetes.54.2.492. Diabetes. 2005. PMID: 15677507
434 results