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Cell lines derived from hippocampal neurons of the normal and trisomy 16 mouse fetus (a model for Down syndrome) exhibit neuronal markers, cholinergic function, and functional neurotransmitter receptors.
Cárdenas AM, Arriagada C, Allen DD, Caviedes R, Cortes JF, Martin J, Couve E, Rapoport SI, Shimahara T, Caviedes P. Cárdenas AM, et al. Among authors: shimahara t. Exp Neurol. 2002 Sep;177(1):159-70. doi: 10.1006/exnr.2002.7957. Exp Neurol. 2002. PMID: 12429219
Knockdown of Myo-Inositol Transporter SMIT1 Normalizes Cholinergic and Glutamatergic Function in an Immortalized Cell Line Established from the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Human Trisomy 21 (Down Syndrome).
Cárdenas AM, Fernández-Olivares P, Díaz-Franulic I, González-Jamett AM, Shimahara T, Segura-Aguilar J, Caviedes R, Caviedes P. Cárdenas AM, et al. Among authors: shimahara t. Neurotox Res. 2017 Nov;32(4):614-623. doi: 10.1007/s12640-017-9775-0. Epub 2017 Jul 10. Neurotox Res. 2017. PMID: 28695546
The catecholaminergic RCSN-3 cell line: a model to study dopamine metabolism.
Paris I, Lozano J, Cardenas S, Perez-Pastene C, Saud K, Fuentes P, Caviedes P, Dagnino-Subiabre A, Raisman-Vozari R, Shimahara T, Kostrzewa JP, Chi D, Kostrzewa RM, Caviedes R, Segura-Aguilar J. Paris I, et al. Among authors: shimahara t. Neurotox Res. 2008 May-Jun;13(3-4):221-30. doi: 10.1007/BF03033505. Neurotox Res. 2008. PMID: 18522901
Cell lines as in vitro models for drug screening and toxicity studies.
Allen DD, Caviedes R, Cárdenas AM, Shimahara T, Segura-Aguilar J, Caviedes PA. Allen DD, et al. Among authors: shimahara t. Drug Dev Ind Pharm. 2005 Sep;31(8):757-68. doi: 10.1080/03639040500216246. Drug Dev Ind Pharm. 2005. PMID: 16221610 Review.
66 results