Shimada T - Search Results

1

Ultracentrifugation-free chromatography-mediated large-scale purification of recombinant adeno-associated virus serotype 1 (rAAV1).

Tomono T, Hirai Y, Okada H, Adachi K, Ishii A, Shimada T, Onodera M, Tamaoka A, Okada T. Tomono T, et al. Among authors: shimada t. Mol Ther Methods Clin Dev. 2016 Feb 10;3:15058. doi: 10.1038/mtm.2015.58. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 26913289 Free PMC article.

2

Highly Efficient Ultracentrifugation-free Chromatographic Purification of Recombinant AAV Serotype 9.

Tomono T, Hirai Y, Okada H, Miyagawa Y, Adachi K, Sakamoto S, Kawano Y, Chono H, Mineno J, Ishii A, Shimada T, Onodera M, Tamaoka A, Okada T. Tomono T, et al. Among authors: shimada t. Mol Ther Methods Clin Dev. 2018 Nov 1;11:180-190. doi: 10.1016/j.omtm.2018.10.015. eCollection 2018 Dec 14. Mol Ther Methods Clin Dev. 2018. PMID: 30533449 Free PMC article.

3

Serotype-independent method of recombinant adeno-associated virus (AAV) vector production and purification.

Miyake K, Miyake N, Yamazaki Y, Shimada T, Hirai Y. Miyake K, et al. Among authors: shimada t. J Nippon Med Sch. 2012;79(6):394-402. doi: 10.1272/jnms.79.394. J Nippon Med Sch. 2012. PMID: 23291836 Free article. Review.

4

Treatment of hypophosphatasia by muscle-directed expression of bone-targeted alkaline phosphatase via self-complementary AAV8 vector.

Nakamura-Takahashi A, Miyake K, Watanabe A, Hirai Y, Iijima O, Miyake N, Adachi K, Nitahara-Kasahara Y, Kinoshita H, Noguchi T, Abe S, Narisawa S, Millán JL, Shimada T, Okada T. Nakamura-Takahashi A, et al. Among authors: shimada t. Mol Ther Methods Clin Dev. 2016 Feb 3;3:15059. doi: 10.1038/mtm.2015.59. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 26904710 Free PMC article.

5

Systemic cancer gene therapy using adeno-associated virus type 1 vector expressing MDA-7/IL24.

Tahara I, Miyake K, Hanawa H, Kurai T, Hirai Y, Ishizaki M, Uchida E, Tajiri T, Shimada T. Tahara I, et al. Among authors: shimada t. Mol Ther. 2007 Oct;15(10):1805-11. doi: 10.1038/sj.mt.6300225. Epub 2007 Jun 5. Mol Ther. 2007. PMID: 17551500 Free article.

6

Treatment with bone maturation and average lifespan of HPP model mice by AAV8-mediated neonatal gene therapy via single muscle injection.

Matsumoto T, Miyake K, Miyake N, Iijima O, Adachi K, Narisawa S, Millán JL, Orimo H, Shimada T. Matsumoto T, et al. Among authors: shimada t. Mol Ther Methods Clin Dev. 2021 Jun 12;22:330-337. doi: 10.1016/j.omtm.2021.06.006. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34514025 Free PMC article.

7

Coexpression of formylglycine-generating enzyme is essential for synthesis and secretion of functional arylsulfatase A in a mouse model of metachromatic leukodystrophy.

Takakusaki Y, Hisayasu S, Hirai Y, Shimada T. Takakusaki Y, et al. Among authors: shimada t. Hum Gene Ther. 2005 Aug;16(8):929-36. doi: 10.1089/hum.2005.16.929. Hum Gene Ther. 2005. PMID: 16076251

8

Direct comparison of four adeno-associated virus serotypes in mediating the production of antiangiogenic proteins in mouse muscle.

Isotani M, Miyake K, Miyake N, Hirai Y, Shimada T. Isotani M, et al. Among authors: shimada t. Cancer Invest. 2011 Jun;29(5):353-9. doi: 10.3109/07357907.2011.584585. Cancer Invest. 2011. PMID: 21599511

9

Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF.

Yamazaki Y, Hirai Y, Miyake K, Shimada T. Yamazaki Y, et al. Among authors: shimada t. Sci Rep. 2014 Jul 1;4:5506. doi: 10.1038/srep05506. Sci Rep. 2014. PMID: 24981028 Free PMC article.

10

Aspects of Gene Therapy Products Using Current Genome-Editing Technology in Japan.

Yamaguchi T, Uchida E, Okada T, Ozawa K, Onodera M, Kume A, Shimada T, Takahashi S, Tani K, Nasu Y, Mashimo T, Mizuguchi H, Mitani K, Maki K. Yamaguchi T, et al. Among authors: shimada t. Hum Gene Ther. 2020 Oct;31(19-20):1043-1053. doi: 10.1089/hum.2020.156. Epub 2020 Sep 17. Hum Gene Ther. 2020. PMID: 32731837 Free PMC article. Review.

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