Shim JS - Search Results

1

BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance.

Shu X, Li J, Chan UI, Su SM, Shi C, Zhang X, An T, Xu J, Mo L, Liu J, Wang Y, Li X, Deng M, Lei JH, Wang C, Tian H, Heng S, Shim JS, Zhang X, Dai Y, Yao Z, Kuang X, Lin Y, Deng CX, Xu X. Shu X, et al. Among authors: shim js. Cancer Res. 2023 Aug 1;83(15):2614-2633. doi: 10.1158/0008-5472.CAN-22-3398. Cancer Res. 2023. PMID: 37227919 Free PMC article.

2

BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition.

Zhang B, Lyu J, Liu Y, Wu C, Yang EJ, Pardeshi L, Tan K, Wong KH, Chen Q, Xu X, Deng CX, Shim JS. Zhang B, et al. Among authors: shim js. Oncogene. 2018 Dec;37(49):6341-6356. doi: 10.1038/s41388-018-0408-8. Epub 2018 Jul 24. Oncogene. 2018. PMID: 30042414

3

Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells.

Zhang B, Lyu J, Yang EJ, Liu Y, Wu C, Pardeshi L, Tan K, Chen Q, Xu X, Deng CX, Shim JS. Zhang B, et al. Among authors: shim js. Acta Pharm Sin B. 2020 Apr;10(4):615-627. doi: 10.1016/j.apsb.2019.08.008. Epub 2019 Sep 5. Acta Pharm Sin B. 2020. PMID: 32322466 Free PMC article.

4

Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT.

Liu Y, Yang EJ, Shi C, Mou PK, Zhang B, Wu C, Lyu J, Shim JS. Liu Y, et al. Among authors: shim js. Int J Biol Sci. 2020 Mar 25;16(11):1774-1784. doi: 10.7150/ijbs.42197. eCollection 2020. Int J Biol Sci. 2020. PMID: 32398948 Free PMC article.

5

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics.

Lyu J, Yang EJ, Zhang B, Wu C, Pardeshi L, Shi C, Mou PK, Liu Y, Tan K, Shim JS. Lyu J, et al. Among authors: shim js. Nat Commun. 2020 Oct 9;11(1):5105. doi: 10.1038/s41467-020-18872-0. Nat Commun. 2020. PMID: 33037191 Free PMC article.

6

Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.

Shi C, Yang EJ, Liu Y, Mou PK, Ren G, Shim JS. Shi C, et al. Among authors: shim js. Oncogene. 2021 Feb;40(5):937-950. doi: 10.1038/s41388-020-01580-w. Epub 2020 Dec 8. Oncogene. 2021. PMID: 33293694

7

Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics.

Ding RB, Chen P, Rajendran BK, Lyu X, Wang H, Bao J, Zeng J, Hao W, Sun H, Wong AH, Valecha MV, Yang EJ, Su SM, Choi TK, Liu S, Chan KI, Yang LL, Wu J, Miao K, Chen Q, Shim JS, Xu X, Deng CX. Ding RB, et al. Among authors: shim js. Nat Commun. 2021 May 24;12(1):3046. doi: 10.1038/s41467-021-23379-3. Nat Commun. 2021. PMID: 34031426 Free PMC article.

8

Aurora kinase A, a synthetic lethal target for precision cancer medicine.

Mou PK, Yang EJ, Shi C, Ren G, Tao S, Shim JS. Mou PK, et al. Among authors: shim js. Exp Mol Med. 2021 May;53(5):835-847. doi: 10.1038/s12276-021-00635-6. Epub 2021 May 28. Exp Mol Med. 2021. PMID: 34050264 Free PMC article. Review.

9

Natural products targeting cancer cell dependency.

Shi C, Yang EJ, Tao S, Ren G, Mou PK, Shim JS. Shi C, et al. Among authors: shim js. J Antibiot (Tokyo). 2021 Oct;74(10):677-686. doi: 10.1038/s41429-021-00438-x. Epub 2021 Jun 23. J Antibiot (Tokyo). 2021. PMID: 34163025 Review.

10

Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation.

Shi C, Tao S, Ren G, Yang EJ, Shu X, Mou PK, Liu Y, Dang Y, Xu X, Shim JS. Shi C, et al. Among authors: shim js. Oncogene. 2022 May;41(19):2734-2748. doi: 10.1038/s41388-022-02293-y. Epub 2022 Apr 7. Oncogene. 2022. PMID: 35393542

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