Shim JS - Search Results

1

Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics.

Ding RB, Chen P, Rajendran BK, Lyu X, Wang H, Bao J, Zeng J, Hao W, Sun H, Wong AH, Valecha MV, Yang EJ, Su SM, Choi TK, Liu S, Chan KI, Yang LL, Wu J, Miao K, Chen Q, Shim JS, Xu X, Deng CX. Ding RB, et al. Among authors: shim js. Nat Commun. 2021 May 24;12(1):3046. doi: 10.1038/s41467-021-23379-3. Nat Commun. 2021. PMID: 34031426 Free PMC article.

2

Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells.

Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng C, Ye Z, Jang YY. Choi SM, et al. Among authors: shim js. Hepatology. 2013 Jun;57(6):2458-68. doi: 10.1002/hep.26237. Hepatology. 2013. PMID: 23325555 Free PMC article.

3

Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism.

Shim JS, Li RJ, Lv J, Head SA, Yang EJ, Liu JO. Shim JS, et al. Cancer Lett. 2015 Jun 28;362(1):106-15. doi: 10.1016/j.canlet.2015.03.022. Epub 2015 Mar 20. Cancer Lett. 2015. PMID: 25799952 Free PMC article.

4

Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole.

Shim JS, Li RJ, Bumpus NN, Head SA, Kumar Pasunooti K, Yang EJ, Lv J, Shi W, Liu JO. Shim JS, et al. Clin Cancer Res. 2016 Jun 1;22(11):2709-20. doi: 10.1158/1078-0432.CCR-15-1888. Epub 2016 Jan 22. Clin Cancer Res. 2016. PMID: 26801248

5

Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis.

Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Head SA, et al. Among authors: shim js. ACS Chem Biol. 2017 Jan 20;12(1):174-182. doi: 10.1021/acschembio.6b00849. Epub 2016 Dec 2. ACS Chem Biol. 2017. PMID: 28103683 Free PMC article.

6

Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.

Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Yang C, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Lyu J, et al. Among authors: shim js. Cancer Lett. 2017 Nov 28;409:91-103. doi: 10.1016/j.canlet.2017.09.009. Epub 2017 Sep 18. Cancer Lett. 2017. PMID: 28923401 Free PMC article.

7

BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition.

Zhang B, Lyu J, Liu Y, Wu C, Yang EJ, Pardeshi L, Tan K, Wong KH, Chen Q, Xu X, Deng CX, Shim JS. Zhang B, et al. Among authors: shim js. Oncogene. 2018 Dec;37(49):6341-6356. doi: 10.1038/s41388-018-0408-8. Epub 2018 Jul 24. Oncogene. 2018. PMID: 30042414

8

Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells.

Wu C, Lyu J, Yang EJ, Liu Y, Zhang B, Shim JS. Wu C, et al. Among authors: shim js. Nat Commun. 2018 Aug 10;9(1):3212. doi: 10.1038/s41467-018-05694-4. Nat Commun. 2018. PMID: 30097580 Free PMC article.

9

PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A.

Liu Y, Yang EJ, Zhang B, Miao Z, Wu C, Lyu J, Tan K, Poon TCW, Shim JS. Liu Y, et al. Among authors: shim js. Cancer Lett. 2018 Nov 1;436:28-37. doi: 10.1016/j.canlet.2018.08.011. Epub 2018 Aug 14. Cancer Lett. 2018. PMID: 30118842

10

Cholesterol Trafficking: An Emerging Therapeutic Target for Angiogenesis and Cancer.

Lyu J, Yang EJ, Shim JS. Lyu J, et al. Among authors: shim js. Cells. 2019 Apr 28;8(5):389. doi: 10.3390/cells8050389. Cells. 2019. PMID: 31035320 Free PMC article. Review.

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