Shim JS - Search Results

1

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.

Liu-Chittenden Y, Huang B, Shim JS, Chen Q, Lee SJ, Anders RA, Liu JO, Pan D. Liu-Chittenden Y, et al. Among authors: shim js. Genes Dev. 2012 Jun 15;26(12):1300-5. doi: 10.1101/gad.192856.112. Epub 2012 Jun 7. Genes Dev. 2012. PMID: 22677547 Free PMC article.

2

Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth.

Lin J, Haffner MC, Zhang Y, Lee BH, Brennen WN, Britton J, Kachhap SK, Shim JS, Liu JO, Nelson WG, Yegnasubramanian S, Carducci MA. Lin J, et al. Among authors: shim js. Prostate. 2011 Mar 1;71(4):333-43. doi: 10.1002/pros.21247. Epub 2010 Aug 31. Prostate. 2011. PMID: 20809552 Free PMC article.

3

Tricyclic thiazoles are a new class of angiogenesis inhibitors.

Bhat S, Shim JS, Liu JO. Bhat S, et al. Among authors: shim js. Bioorg Med Chem Lett. 2013 May 1;23(9):2733-7. doi: 10.1016/j.bmcl.2013.02.067. Epub 2013 Feb 24. Bioorg Med Chem Lett. 2013. PMID: 23518276 Free PMC article.

4

Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.

Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Zhang F, et al. Among authors: shim js. J Med Chem. 2013 May 23;56(10):3996-4016. doi: 10.1021/jm400227z. Epub 2013 May 1. J Med Chem. 2013. PMID: 23634668 Free PMC article.

5

Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer.

Wang M, Shim JS, Li RJ, Dang Y, He Q, Das M, Liu JO. Wang M, et al. Among authors: shim js. Br J Pharmacol. 2014 Oct;171(19):4478-89. doi: 10.1111/bph.12800. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24903412 Free PMC article.

6

Recent advances in drug repositioning for the discovery of new anticancer drugs.

Shim JS, Liu JO. Shim JS, et al. Int J Biol Sci. 2014 Jun 10;10(7):654-63. doi: 10.7150/ijbs.9224. eCollection 2014. Int J Biol Sci. 2014. PMID: 25013375 Free PMC article. Review.

7

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.

He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Lane BS, Shim JS, Zeng LF, He Y, Chen L, Wells CD, Liu JO, Zhang ZY. He R, et al. Among authors: shim js. ACS Med Chem Lett. 2015 Jun 8;6(7):782-6. doi: 10.1021/acsmedchemlett.5b00118. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191366 Free PMC article.

8

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.

Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Head SA, et al. Among authors: shim js. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7276-85. doi: 10.1073/pnas.1512867112. Epub 2015 Dec 10. Proc Natl Acad Sci U S A. 2015. PMID: 26655341 Free PMC article.

9

Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole.

Shim JS, Li RJ, Bumpus NN, Head SA, Kumar Pasunooti K, Yang EJ, Lv J, Shi W, Liu JO. Shim JS, et al. Clin Cancer Res. 2016 Jun 1;22(11):2709-20. doi: 10.1158/1078-0432.CCR-15-1888. Epub 2016 Jan 22. Clin Cancer Res. 2016. PMID: 26801248

10

Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis.

Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Head SA, et al. Among authors: shim js. ACS Chem Biol. 2017 Jan 20;12(1):174-182. doi: 10.1021/acschembio.6b00849. Epub 2016 Dec 2. ACS Chem Biol. 2017. PMID: 28103683 Free PMC article.

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