Shim JH - Search Results

1

AAV-Mediated Targeting of the Activin A-ACVR1^R206H Signaling in Fibrodysplasia Ossificans Progressiva.

Yang YS, Lin C, Ma H, Xie J, Kaplan FS, Gao G, Shim JH. Yang YS, et al. Among authors: shim jh. Biomolecules. 2023 Sep 8;13(9):1364. doi: 10.3390/biom13091364. Biomolecules. 2023. PMID: 37759764 Free PMC article.

2

Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery.

Yang YS, Kim JM, Xie J, Chaugule S, Lin C, Ma H, Hsiao E, Hong J, Chun H, Shore EM, Kaplan FS, Gao G, Shim JH. Yang YS, et al. Among authors: shim jh. Nat Commun. 2022 Oct 19;13(1):6175. doi: 10.1038/s41467-022-33956-9. Nat Commun. 2022. PMID: 36258013 Free PMC article.

3

Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis.

Yang YS, Xie J, Wang D, Kim JM, Tai PWL, Gravallese E, Gao G, Shim JH. Yang YS, et al. Among authors: shim jh. Nat Commun. 2019 Jul 4;10(1):2958. doi: 10.1038/s41467-019-10809-6. Nat Commun. 2019. PMID: 31273195 Free PMC article.

4

Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy.

Yang YS, Xie J, Chaugule S, Wang D, Kim JM, Kim J, Tai PWL, Seo SK, Gravallese E, Gao G, Shim JH. Yang YS, et al. Among authors: shim jh. Mol Ther Methods Clin Dev. 2020 Apr 18;17:922-935. doi: 10.1016/j.omtm.2020.04.010. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32405514 Free PMC article.

5

Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes.

Kim JM, Yang YS, Xie J, Lee O, Kim J, Hong J, Boldyreff B, Filhol O, Chun H, Greenblatt MB, Gao G, Shim JH. Kim JM, et al. Among authors: shim jh. Cell Death Differ. 2022 Aug;29(8):1625-1638. doi: 10.1038/s41418-022-00952-x. Epub 2022 Feb 15. Cell Death Differ. 2022. PMID: 35169297 Free PMC article.

6

Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles.

Eekhoff EMW, de Ruiter RD, Smilde BJ, Schoenmaker T, de Vries TJ, Netelenbos C, Hsiao EC, Scott C, Haga N, Grunwald Z, De Cunto CL, di Rocco M, Delai PLR, Diecidue RJ, Madhuri V, Cho TJ, Morhart R, Friedman CS, Zasloff M, Pals G, Shim JH, Gao G, Kaplan F, Pignolo RJ, Micha D. Eekhoff EMW, et al. Among authors: shim jh. Hum Gene Ther. 2022 Aug;33(15-16):782-788. doi: 10.1089/hum.2022.023. Hum Gene Ther. 2022. PMID: 35502479 Free PMC article. Review.

7

AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy.

John AA, Xie J, Yang YS, Kim JM, Lin C, Ma H, Gao G, Shim JH. John AA, et al. Among authors: shim jh. Mol Ther Nucleic Acids. 2022 Jul 11;29:296-311. doi: 10.1016/j.omtn.2022.07.008. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 35950212 Free PMC article.

8

WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects.

Oh WT, Yang YS, Xie J, Ma H, Kim JM, Park KH, Oh DS, Park-Min KH, Greenblatt MB, Gao G, Shim JH. Oh WT, et al. Among authors: shim jh. Mol Ther. 2023 Feb 1;31(2):435-453. doi: 10.1016/j.ymthe.2022.09.018. Epub 2022 Oct 3. Mol Ther. 2023. PMID: 36184851 Free PMC article.

9

Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.

Lin C, Yang Q, Guo D, Xie J, Yang YS, Chaugule S, DeSouza N, Oh WT, Li R, Chen Z, John AA, Qiu Q, Zhu LJ, Greenblatt MB, Ghosh S, Li S, Gao G, Haynes C, Emerson CP, Shim JH. Lin C, et al. Among authors: shim jh. Nat Commun. 2022 Nov 11;13(1):6869. doi: 10.1038/s41467-022-34694-8. Nat Commun. 2022. PMID: 36369293 Free PMC article.

10

Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis.

Stavre Z, Kim JM, Yang YS, Nündel K, Chaugule S, Sato T, Park KH, Gao G, Gravallese EM, Shim JH. Stavre Z, et al. Among authors: shim jh. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2218019120. doi: 10.1073/pnas.2218019120. Epub 2023 May 4. Proc Natl Acad Sci U S A. 2023. PMID: 37141171 Free PMC article.

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