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CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts.
Greenblatt MB, Park KH, Oh H, Kim JM, Shin DY, Lee JM, Lee JW, Singh A, Lee KY, Hu D, Xiao C, Charles JF, Penninger JM, Lotinun S, Baron R, Ghosh S, Shim JH. Greenblatt MB, et al. Among authors: shim jh. J Exp Med. 2015 Jul 27;212(8):1283-301. doi: 10.1084/jem.20150407. Epub 2015 Jul 20. J Exp Med. 2015. PMID: 26195726 Free PMC article.
Targeting skeletal endothelium to ameliorate bone loss.
Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim JH, Glimcher LH, Greenblatt MB. Xu R, et al. Among authors: shim jh. Nat Med. 2018 Jun;24(6):823-833. doi: 10.1038/s41591-018-0020-z. Epub 2018 May 21. Nat Med. 2018. PMID: 29785024 Free PMC article.
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. Kim JM, et al. Among authors: shim jh. Nat Commun. 2020 May 8;11(1):2289. doi: 10.1038/s41467-020-16038-6. Nat Commun. 2020. PMID: 32385263 Free PMC article.
Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy.
Yang YS, Xie J, Chaugule S, Wang D, Kim JM, Kim J, Tai PWL, Seo SK, Gravallese E, Gao G, Shim JH. Yang YS, et al. Among authors: shim jh. Mol Ther Methods Clin Dev. 2020 Apr 18;17:922-935. doi: 10.1016/j.omtm.2020.04.010. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32405514 Free PMC article.
TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.
Li Z, Oh H, Cung M, Marquez SJ, Sun J, Hammad H, Janssens S, Pouliot P, Lambrecht BN, Yang YS, Shim JH, Greenblatt MB. Li Z, et al. Among authors: shim jh. Biochem Biophys Res Commun. 2020 Oct 22;531(4):497-502. doi: 10.1016/j.bbrc.2020.07.060. Epub 2020 Aug 14. Biochem Biophys Res Commun. 2020. PMID: 32807497 Free PMC article.
Osteoblast-Osteoclast Communication and Bone Homeostasis.
Kim JM, Lin C, Stavre Z, Greenblatt MB, Shim JH. Kim JM, et al. Among authors: shim jh. Cells. 2020 Sep 10;9(9):2073. doi: 10.3390/cells9092073. Cells. 2020. PMID: 32927921 Free PMC article. Review.
1,253 results