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Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.
Zeeshan M, Shilliday F, Liu T, Abel S, Mourier T, Ferguson DJP, Rea E, Stanway RR, Roques M, Williams D, Daniel E, Brady D, Roberts AJ, Holder AA, Pain A, Le Roch KG, Moores CA, Tewari R. Zeeshan M, et al. Among authors: shilliday f. PLoS Pathog. 2019 Oct 10;15(10):e1008048. doi: 10.1371/journal.ppat.1008048. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31600347 Free PMC article.
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.
Gaillard N, Sharma A, Abbaali I, Liu T, Shilliday F, Cook AD, Ehrhard V, Bangera M, Roberts AJ, Moores CA, Morrissette N, Steinmetz MO. Gaillard N, et al. Among authors: shilliday f. EMBO Mol Med. 2021 Nov 8;13(11):e13818. doi: 10.15252/emmm.202013818. Epub 2021 Oct 18. EMBO Mol Med. 2021. PMID: 34661376 Free PMC article.
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders.
Lucas SCC, Ahmed A, Ashraf SN, Argyrou A, Bauer MR, De Donatis GM, Demanze S, Eisele F, Fusani L, Hock A, Kadamur G, Li S, Macmillan-Jones A, Michaelides IN, Phillips C, Rehnström M, Richter M, Rodrigo-Brenni MC, Shilliday F, Wang P, Storer RI. Lucas SCC, et al. Among authors: shilliday f. J Med Chem. 2024 Apr 11;67(7):5538-5566. doi: 10.1021/acs.jmedchem.3c02136. Epub 2024 Mar 21. J Med Chem. 2024. PMID: 38513086
Cryo-EM: The Resolution Revolution and Drug Discovery.
de Oliveira TM, van Beek L, Shilliday F, Debreczeni JÉ, Phillips C. de Oliveira TM, et al. Among authors: shilliday f. SLAS Discov. 2021 Jan;26(1):17-31. doi: 10.1177/2472555220960401. Epub 2020 Oct 5. SLAS Discov. 2021. PMID: 33016175 Free article. Review.
17 results