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2015 Guidance on cancer immunotherapy development in early-phase clinical studies.
Guidance Development Review Committee; Working Group for Clinical Studies of Cancer Immunotherapy; Working Group for Effector Cell Therapy; Working Group for CMC/Non-clinical Studies; Working Group for Cancer Vaccines and Adjuvants; Working Group for Anti-immune Checkpoint Therapy and Comprehensive Cancer Immunotherapy; Biostatistics Subcommittee. Guidance Development Review Committee, et al. Cancer Sci. 2015 Dec;106(12):1761-71. doi: 10.1111/cas.12819. Cancer Sci. 2015. PMID: 26767933 Free PMC article.
Exhaustion, rather than lack of infiltration and persistence, of CAR-T cells hampers the efficacy of CAR-T therapy in an orthotopic PDAC xenograft model.
Takeuchi Y, Wang Y, Sasaki K, Sato O, Tsuchikawa T, Wang L, Amaishi Y, Okamoto S, Mineno J, Hirokawa Y, Hatanaka KC, Hatanaka Y, Kato T, Shiku H, Hirano S. Takeuchi Y, et al. Among authors: shiku h. Biomed Pharmacother. 2024 Jan;170:116052. doi: 10.1016/j.biopha.2023.116052. Epub 2023 Dec 22. Biomed Pharmacother. 2024. PMID: 38141280 Free article.
Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4.
Alsalloum A, Shevchenko J, Fisher M, Philippova J, Perik-Zavodskii R, Perik-Zavodskaia O, Alrhmoun S, Lopatnikova J, Vasily K, Volynets M, Zavjalov E, Solovjeva O, Akahori Y, Shiku H, Silkov A, Sennikov S. Alsalloum A, et al. Among authors: shiku h. Int J Mol Sci. 2023 Oct 13;24(20):15134. doi: 10.3390/ijms242015134. Int J Mol Sci. 2023. PMID: 37894816 Free PMC article.
723 results