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The Gallus gallus RJF reference genome reveals an MHCY haplotype organized in gene blocks that contain 107 loci including 45 specialized, polymorphic MHC class I loci, 41 C-type lectin-like loci, and other loci amid hundreds of transposable elements.
Goto RM, Warden CD, Shiina T, Hosomichi K, Zhang J, Kang TH, Wu X, Glass MC, Delany ME, Miller MM. Goto RM, et al. Among authors: shiina t. G3 (Bethesda). 2022 Nov 4;12(11):jkac218. doi: 10.1093/g3journal/jkac218. G3 (Bethesda). 2022. PMID: 35997588 Free PMC article.
Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Shiina T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, Gojobori T, Inoko H, Bahram S. Shiina T, et al. Genetics. 2006 Jul;173(3):1555-70. doi: 10.1534/genetics.106.057034. Epub 2006 May 15. Genetics. 2006. PMID: 16702430 Free PMC article.
596 results