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Structure of the bile acid transporter and HBV receptor NTCP.
Asami J, Kimura KT, Fujita-Fujiharu Y, Ishida H, Zhang Z, Nomura Y, Liu K, Uemura T, Sato Y, Ono M, Yamamoto M, Noda T, Shigematsu H, Drew D, Iwata S, Shimizu T, Nomura N, Ohto U. Asami J, et al. Among authors: shigematsu h. Nature. 2022 Jun;606(7916):1021-1026. doi: 10.1038/s41586-022-04845-4. Epub 2022 May 17. Nature. 2022. PMID: 35580629
Structural analysis reveals TLR7 dynamics underlying antagonism.
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T. Tojo S, et al. Among authors: shigematsu h. Nat Commun. 2020 Oct 15;11(1):5204. doi: 10.1038/s41467-020-19025-z. Nat Commun. 2020. PMID: 33060576 Free PMC article.
Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein.
Nojima S, Fujita Y, Kimura KT, Nomura N, Suno R, Morimoto K, Yamamoto M, Noda T, Iwata S, Shigematsu H, Kobayashi T. Nojima S, et al. Among authors: shigematsu h. Structure. 2021 Mar 4;29(3):252-260.e6. doi: 10.1016/j.str.2020.11.007. Epub 2020 Dec 1. Structure. 2021. PMID: 33264604 Free article.
Cryo-EM structures of Toll-like receptors in complex with UNC93B1.
Ishida H, Asami J, Zhang Z, Nishizawa T, Shigematsu H, Ohto U, Shimizu T. Ishida H, et al. Among authors: shigematsu h. Nat Struct Mol Biol. 2021 Feb;28(2):173-180. doi: 10.1038/s41594-020-00542-w. Epub 2021 Jan 11. Nat Struct Mol Biol. 2021. PMID: 33432245
Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K, Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T, Fujiwara T. Tanaka M, et al. Among authors: shigematsu h. Nat Chem Biol. 2024 May;20(5):605-614. doi: 10.1038/s41589-023-01513-0. Epub 2024 Jan 24. Nat Chem Biol. 2024. PMID: 38267667
Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Yamagata A, Miyazaki Y, Yokoi N, Shigematsu H, Sato Y, Goto-Ito S, Maeda A, Goto T, Sanbo M, Hirabayashi M, Shirouzu M, Fukata Y, Fukata M, Fukai S. Yamagata A, et al. Among authors: shigematsu h. Nat Commun. 2018 Apr 18;9(1):1546. doi: 10.1038/s41467-018-03947-w. Nat Commun. 2018. PMID: 29670100 Free PMC article.
Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nishida Y, Yanagisawa S, Morita R, Shigematsu H, Shinzawa-Itoh K, Yuki H, Ogasawara S, Shimuta K, Iwamoto T, Nakabayashi C, Matsumura W, Kato H, Gopalasingam C, Nagao T, Qaqorh T, Takahashi Y, Yamazaki S, Kamiya K, Harada R, Mizuno N, Takahashi H, Akeda Y, Ohnishi M, Ishii Y, Kumasaka T, Murata T, Muramoto K, Tosha T, Shiro Y, Honma T, Shigeta Y, Kubo M, Takashima S, Shintani Y. Nishida Y, et al. Among authors: shigematsu h. Nat Commun. 2022 Dec 8;13(1):7591. doi: 10.1038/s41467-022-34771-y. Nat Commun. 2022. PMID: 36481732 Free PMC article.
853 results