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High mortality rates among solid organ transplant recipients infected with extensively drug-resistant Acinetobacter baumannii: using in vitro antibiotic combination testing to identify the combination of a carbapenem and colistin as an effective treatment regimen.
Shields RK, Kwak EJ, Potoski BA, Doi Y, Adams-Haduch JM, Silviera FP, Toyoda Y, Pilewski JM, Crespo M, Pasculle AW, Clancy CJ, Nguyen MH. Shields RK, et al. Diagn Microbiol Infect Dis. 2011 Jun;70(2):246-52. doi: 10.1016/j.diagmicrobio.2010.12.023. Epub 2011 Feb 25. Diagn Microbiol Infect Dis. 2011. PMID: 21353436
Characterization of porin expression in Klebsiella pneumoniae Carbapenemase (KPC)-producing K. pneumoniae identifies isolates most susceptible to the combination of colistin and carbapenems.
Hong JH, Clancy CJ, Cheng S, Shields RK, Chen L, Doi Y, Zhao Y, Perlin DS, Kreiswirth BN, Nguyen MH. Hong JH, et al. Among authors: shields rk. Antimicrob Agents Chemother. 2013 May;57(5):2147-53. doi: 10.1128/AAC.02411-12. Epub 2013 Mar 4. Antimicrob Agents Chemother. 2013. PMID: 23459476 Free PMC article.
Mutations of the ompK36 porin gene and promoter impact responses of sequence type 258, KPC-2-producing Klebsiella pneumoniae strains to doripenem and doripenem-colistin.
Clancy CJ, Chen L, Hong JH, Cheng S, Hao B, Shields RK, Farrell AN, Doi Y, Zhao Y, Perlin DS, Kreiswirth BN, Nguyen MH. Clancy CJ, et al. Among authors: shields rk. Antimicrob Agents Chemother. 2013 Nov;57(11):5258-65. doi: 10.1128/AAC.01069-13. Epub 2013 Aug 12. Antimicrob Agents Chemother. 2013. PMID: 23939888 Free PMC article.
Epidemiology and molecular characterization of bacteremia due to carbapenem-resistant Klebsiella pneumoniae in transplant recipients.
Clancy CJ, Chen L, Shields RK, Zhao Y, Cheng S, Chavda KD, Hao B, Hong JH, Doi Y, Kwak EJ, Silveira FP, Abdel-Massih R, Bogdanovich T, Humar A, Perlin DS, Kreiswirth BN, Hong Nguyen M. Clancy CJ, et al. Among authors: shields rk. Am J Transplant. 2013 Oct;13(10):2619-33. doi: 10.1111/ajt.12424. Epub 2013 Sep 6. Am J Transplant. 2013. PMID: 24011185 Free PMC article. Clinical Trial.
Carbapenem-resistant Klebsiella pneumoniae strains exhibit diversity in aminoglycoside-modifying enzymes, which exert differing effects on plazomicin and other agents.
Almaghrabi R, Clancy CJ, Doi Y, Hao B, Chen L, Shields RK, Press EG, Iovine NM, Townsend BM, Wagener MM, Kreiswirth B, Nguyen MH. Almaghrabi R, et al. Among authors: shields rk. Antimicrob Agents Chemother. 2014 Aug;58(8):4443-51. doi: 10.1128/AAC.00099-14. Epub 2014 May 27. Antimicrob Agents Chemother. 2014. PMID: 24867988 Free PMC article.
297 results