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Identification of aceNKPs, a committed common progenitor population of the ILC1 and NK cell continuum.
Rodriguez-Rodriguez N, Clark PA, Gogoi M, Ferreira ACF, Kerscher B, Crisp A, Jolin HE, Murphy JE, Sivasubramaniam M, Pedro L, Walker JA, Heycock MWD, Shields JD, Barlow JL, McKenzie ANJ. Rodriguez-Rodriguez N, et al. Among authors: shields jd. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2203454119. doi: 10.1073/pnas.2203454119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442116 Free PMC article.
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Muliaditan T, Caron J, Okesola M, Opzoomer JW, Kosti P, Georgouli M, Gordon P, Lall S, Kuzeva DM, Pedro L, Shields JD, Gillett CE, Diebold SS, Sanz-Moreno V, Ng T, Hoste E, Arnold JN. Muliaditan T, et al. Among authors: shields jd. Nat Commun. 2018 Jul 27;9(1):2951. doi: 10.1038/s41467-018-05346-7. Nat Commun. 2018. PMID: 30054470 Free PMC article.
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Schuijs MJ, Png S, Richard AC, Tsyben A, Hamm G, Stockis J, Garcia C, Pinaud S, Nicholls A, Ros XR, Su J, Eldridge MD, Riedel A, Serrao EM, Rodewald HR, Mack M, Shields JD, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle KM, Marioni JC, Halim TYF. Schuijs MJ, et al. Among authors: shields jd. Nat Immunol. 2020 Sep;21(9):998-1009. doi: 10.1038/s41590-020-0745-y. Epub 2020 Aug 3. Nat Immunol. 2020. PMID: 32747815 Free PMC article.
Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma.
Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JD. Riedel A, et al. Among authors: shields jd. Cancer Immunol Res. 2022 Apr 1;10(4):482-497. doi: 10.1158/2326-6066.CIR-21-0778. Cancer Immunol Res. 2022. PMID: 35362044 Free PMC article.
Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth.
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, Kar G, Vento-Tormo R, Hagai T, Chen X, Haniffa MA, Shields JD, Teichmann SA. Davidson S, et al. Among authors: shields jd. Cell Rep. 2020 May 19;31(7):107628. doi: 10.1016/j.celrep.2020.107628. Cell Rep. 2020. PMID: 32433953 Free PMC article.
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Mahata B, Pramanik J, van der Weyden L, Polanski K, Kar G, Riedel A, Chen X, Fonseca NA, Kundu K, Campos LS, Ryder E, Duddy G, Walczak I, Okkenhaug K, Adams DJ, Shields JD, Teichmann SA. Mahata B, et al. Among authors: shields jd. Nat Commun. 2020 Jul 17;11(1):3588. doi: 10.1038/s41467-020-17339-6. Nat Commun. 2020. PMID: 32680985 Free PMC article.
103 results