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Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei.
Kido Y, Shiba T, Inaoka DK, Sakamoto K, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Moore A, Harada S, Kita K. Kido Y, et al. Among authors: shiba t. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):275-8. doi: 10.1107/S1744309109054062. Epub 2010 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208159 Free PMC article.
Structure of the trypanosome cyanide-insensitive alternative oxidase.
Shiba T, Kido Y, Sakamoto K, Inaoka DK, Tsuge C, Tatsumi R, Takahashi G, Balogun EO, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Saimoto H, Moore AL, Harada S, Kita K. Shiba T, et al. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4580-5. doi: 10.1073/pnas.1218386110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487766 Free PMC article.
Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis.
Young L, May B, Pendlebury-Watt A, Shearman J, Elliott C, Albury MS, Shiba T, Inaoka DK, Harada S, Kita K, Moore AL. Young L, et al. Among authors: shiba t. Biochim Biophys Acta. 2014 Jul;1837(7):1219-25. doi: 10.1016/j.bbabio.2014.01.027. Epub 2014 Feb 12. Biochim Biophys Acta. 2014. PMID: 24530866 Free article.
Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Balogun EO, Inaoka DK, Shiba T, Tokuoka SM, Tokumasu F, Sakamoto K, Kido Y, Michels PAM, Watanabe YI, Harada S, Kita K. Balogun EO, et al. Among authors: shiba t. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2830-2842. doi: 10.1016/j.bbagen.2017.07.028. Epub 2017 Aug 2. Biochim Biophys Acta Gen Subj. 2017. PMID: 28778484
Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target.
Hartuti ED, Inaoka DK, Komatsuya K, Miyazaki Y, Miller RJ, Xinying W, Sadikin M, Prabandari EE, Waluyo D, Kuroda M, Amalia E, Matsuo Y, Nugroho NB, Saimoto H, Pramisandi A, Watanabe YI, Mori M, Shiomi K, Balogun EO, Shiba T, Harada S, Nozaki T, Kita K. Hartuti ED, et al. Among authors: shiba t. Biochim Biophys Acta Bioenerg. 2018 Mar;1859(3):191-200. doi: 10.1016/j.bbabio.2017.12.004. Epub 2017 Dec 18. Biochim Biophys Acta Bioenerg. 2018. PMID: 29269266 Free article.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
Balogun EO, Inaoka DK, Shiba T, Tsuge C, May B, Sato T, Kido Y, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PAM, Watanabe YI, Moore AL, Harada S, Kita K. Balogun EO, et al. Among authors: shiba t. FASEB J. 2019 Nov;33(11):13002-13013. doi: 10.1096/fj.201901342R. Epub 2019 Sep 16. FASEB J. 2019. PMID: 31525300
Although the EC(50) of compound 17b against trypanosome cells was 1.77 M, it had no effect on cultured human cells, even at 50 M.-Balogun, E. O., Inaoka, D. K., Shiba, T., Tsuge, C., May, B., Sato, T., Kido, Y., Nara, T., Aoki, T., Honma, T …
Although the EC(50) of compound 17b against trypanosome cells was 1.77 M, it had no effect on cultured human cells, even at 50 M.-Balogun, E …
The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.
Mochizuki K, Inaoka DK, Mazet M, Shiba T, Fukuda K, Kurasawa H, Millerioux Y, Boshart M, Balogun EO, Harada S, Hirayama K, Bringaud F, Kita K. Mochizuki K, et al. Among authors: shiba t. Biochim Biophys Acta Bioenerg. 2020 Nov 1;1861(11):148283. doi: 10.1016/j.bbabio.2020.148283. Epub 2020 Aug 4. Biochim Biophys Acta Bioenerg. 2020. PMID: 32763239 Free PMC article.
798 results