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Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Qi C, et al. Among authors: shi y. Proc Natl Acad Sci U S A. 2023 Dec 19;120(51):e2306767120. doi: 10.1073/pnas.2306767120. Epub 2023 Dec 15. Proc Natl Acad Sci U S A. 2023. PMID: 38100415 Free PMC article.
Novel tau filament fold in corticobasal degeneration.
Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Zhang W, et al. Among authors: shi y. Nature. 2020 Apr;580(7802):283-287. doi: 10.1038/s41586-020-2043-0. Epub 2020 Feb 12. Nature. 2020. PMID: 32050258 Free PMC article.
Structures of α-synuclein filaments from multiple system atrophy.
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Schweighauser M, et al. Among authors: shi y. Nature. 2020 Sep;585(7825):464-469. doi: 10.1038/s41586-020-2317-6. Epub 2020 May 27. Nature. 2020. PMID: 32461689 Free PMC article.
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW. Schweighauser M, et al. Among authors: shi y. Nature. 2022 May;605(7909):310-314. doi: 10.1038/s41586-022-04650-z. Epub 2022 Mar 28. Nature. 2022. PMID: 35344985 Free PMC article.
Structure-based classification of tauopathies.
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Shi Y, et al. Nature. 2021 Oct;598(7880):359-363. doi: 10.1038/s41586-021-03911-7. Epub 2021 Sep 29. Nature. 2021. PMID: 34588692 Free PMC article.
Structures of α-synuclein filaments from human brains with Lewy pathology.
Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M. Yang Y, et al. Among authors: shi y. Nature. 2022 Oct;610(7933):791-795. doi: 10.1038/s41586-022-05319-3. Epub 2022 Sep 15. Nature. 2022. PMID: 36108674 Free PMC article.
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Shi Y, et al. Acta Neuropathol. 2021 May;141(5):697-708. doi: 10.1007/s00401-021-02294-3. Epub 2021 Mar 16. Acta Neuropathol. 2021. PMID: 33723967 Free PMC article.
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy.
Yang Y, Garringer HJ, Shi Y, Lövestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SHW, Goedert M. Yang Y, et al. Among authors: shi y. Acta Neuropathol. 2023 May;145(5):561-572. doi: 10.1007/s00401-023-02550-8. Epub 2023 Feb 27. Acta Neuropathol. 2023. PMID: 36847833 Free PMC article.
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