Shi H - Search Results

1

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.

Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Among authors: shi h. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.

2

TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.

Wang X, Zeldin S, Shi H, Zhu C, Saito Y, Corey KE, Osganian SA, Remotti HE, Verna EC, Pajvani UB, Schwabe RF, Tabas I. Wang X, et al. Among authors: shi h. J Hepatol. 2022 Apr;76(4):910-920. doi: 10.1016/j.jhep.2021.11.031. Epub 2021 Dec 11. J Hepatol. 2022. PMID: 34902531 Free PMC article.

3

The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver.

Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, Hamberger F, Brundu F, Chen Y, Ravichandra A, Huebener P, Anke H, Shi H, Martínez García de la Torre RA, Smith JR, Henderson NC, Vondran FWR, Rothlin CV, Baehre H, Tabas I, Sancho-Bru P, Schwabe RF. Mederacke I, et al. Among authors: shi h. Sci Transl Med. 2022 Apr 6;14(639):eabe5795. doi: 10.1126/scitranslmed.abe5795. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35385339 Free PMC article.

4

CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis.

Shi H, Wang X, Li F, Gerlach BD, Yurdagul A Jr, Moore MP, Zeldin S, Zhang H, Cai B, Zheng Z, Valenti L, Tabas I. Shi H, et al. Sci Transl Med. 2022 Nov 23;14(672):eabp8309. doi: 10.1126/scitranslmed.abp8309. Epub 2022 Nov 23. Sci Transl Med. 2022. PMID: 36417485 Free PMC article.

5

Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH.

Moore MP, Wang X, Shi H, Meroni M, Cherubini A, Ronzoni L, Parks EJ, Ibdah JA, Rector RS, Valenti L, Dongiovanni P, Tabas I. Moore MP, et al. Among authors: shi h. JHEP Rep. 2023 Feb 26;5(5):100716. doi: 10.1016/j.jhepr.2023.100716. eCollection 2023 May. JHEP Rep. 2023. PMID: 37035456 Free PMC article.

6

The role of efferocytosis-fueled macrophage metabolism in the resolution of inflammation.

Schilperoort M, Ngai D, Sukka SR, Avrampou K, Shi H, Tabas I. Schilperoort M, et al. Among authors: shi h. Immunol Rev. 2023 Oct;319(1):65-80. doi: 10.1111/imr.13214. Epub 2023 May 9. Immunol Rev. 2023. PMID: 37158427 Review.

7

Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers.

Wang X, Moore MP, Shi H, Miyata Y, Donnelly SK, Radiloff DR, Tabas I. Wang X, et al. Among authors: shi h. Mol Ther Methods Clin Dev. 2023 Nov 23;31:101165. doi: 10.1016/j.omtm.2023.101165. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38144682 Free PMC article.

8

Efferocytosis in liver disease.

Shi H, Moore MP, Wang X, Tabas I. Shi H, et al. JHEP Rep. 2023 Nov 16;6(1):100960. doi: 10.1016/j.jhepr.2023.100960. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38234410 Free PMC article. Review.

9

Different Types of Dietary Fat and Fructose Interactions Result in Distinct Metabolic Phenotypes in Male Mice.

Shi H, Prough RA, McClain CJ, Song M. Shi H, et al. J Nutr Biochem. 2023 Jan;111:109189. doi: 10.1016/j.jnutbio.2022.109189. Epub 2022 Oct 19. J Nutr Biochem. 2023. PMID: 36272691 Free article.

10

Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes.

Shi H, Jan J, Hardesty JE, Falkner KC, Prough RA, Balamurugan AN, Mokshagundam SP, Chari ST, Cave MC. Shi H, et al. Toxicol Appl Pharmacol. 2019 Jan 15;363:22-33. doi: 10.1016/j.taap.2018.10.011. Epub 2018 Oct 9. Toxicol Appl Pharmacol. 2019. PMID: 30312631 Free PMC article.

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