Shevell DE - Search Results

1

Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension.

Bauman DR, Whitehead A, Contino LC, Cui J, Garcia-Calvo M, Gu X, Kevin N, Ma X, Pai LY, Shah K, Shen X, Stribling S, Zokian HJ, Metzger J, Shevell DE, Waddell ST. Bauman DR, et al. Among authors: shevell de. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3650-3. doi: 10.1016/j.bmcl.2013.03.011. Epub 2013 Mar 22. Bioorg Med Chem Lett. 2013. PMID: 23659858

2

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA. Garcia-Calvo M, et al. Among authors: shevell de. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. doi: 10.1073/pnas.0500269102. Epub 2005 May 31. Proc Natl Acad Sci U S A. 2005. PMID: 15928087 Free PMC article.

3

Discovery and Clinical Evaluation of MK-8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release.

Knox CD, de Kam PJ, Azer K, Wong P, Ederveen AG, Shevell D, Morabito C, Meehan AG, Liu W, Reynders T, Denef JF, Mitselos A, Jonathan D, Gutstein DE, Mitra K, Sun SY, Lo MM, Cully D, Ali A. Knox CD, et al. Among authors: shevell d, de kam pj. J Am Heart Assoc. 2016 Aug 25;5(9):e003493. doi: 10.1161/JAHA.116.003493. J Am Heart Assoc. 2016. PMID: 27561272 Free PMC article.

4

Small molecule antagonists of complement receptor type 3 block adhesion and adhesion-dependent oxidative burst in human polymorphonuclear leukocytes.

Bansal VS, Vaidya S, Somers EP, Kanuga M, Shevell D, Weikel R, Detmers PA. Bansal VS, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1016-24. doi: 10.1124/jpet.102.045286. J Pharmacol Exp Ther. 2003. PMID: 12604677

5

Deficiency in inducible nitric oxide synthase results in reduced atherosclerosis in apolipoprotein E-deficient mice.

Detmers PA, Hernandez M, Mudgett J, Hassing H, Burton C, Mundt S, Chun S, Fletcher D, Card DJ, Lisnock J, Weikel R, Bergstrom JD, Shevell DE, Hermanowski-Vosatka A, Sparrow CP, Chao YS, Rader DJ, Wright SD, Puré E. Detmers PA, et al. Among authors: shevell de. J Immunol. 2000 Sep 15;165(6):3430-5. doi: 10.4049/jimmunol.165.6.3430. J Immunol. 2000. PMID: 10975863

6

A region of the Ada DNA-repair protein required for the activation of ada transcription is not necessary for activation of alkA.

Shevell DE, Walker GC. Shevell DE, et al. Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):9001-5. doi: 10.1073/pnas.88.20.9001. Proc Natl Acad Sci U S A. 1991. PMID: 1924363 Free PMC article.

7

Resistance to alkylation damage in Escherichia coli: role of the Ada protein in induction of the adaptive response.

Shevell DE, Friedman BM, Walker GC. Shevell DE, et al. Mutat Res. 1990 Nov-Dec;233(1-2):53-72. doi: 10.1016/0027-5107(90)90151-s. Mutat Res. 1990. PMID: 2233813 Review. No abstract available.

8

Alteration of the carboxyl-terminal domain of Ada protein influences its inducibility, specificity, and strength as a transcriptional activator.

Shevell DE, LeMotte PK, Walker GC. Shevell DE, et al. J Bacteriol. 1988 Nov;170(11):5263-71. doi: 10.1128/jb.170.11.5263-5271.1988. J Bacteriol. 1988. PMID: 3141384 Free PMC article.

9

Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNA.

Shevell DE, Abou-Zamzam AM, Demple B, Walker GC. Shevell DE, et al. J Bacteriol. 1988 Jul;170(7):3294-6. doi: 10.1128/jb.170.7.3294-3296.1988. J Bacteriol. 1988. PMID: 3290202 Free PMC article.

10

Alteration of lysine 178 in the hinge region of the Escherichia coli ada protein interferes with activation of ada, but not alkA, transcription.

Saget BM, Shevell DE, Walker GC. Saget BM, et al. Among authors: shevell de. J Bacteriol. 1995 Mar;177(5):1268-74. doi: 10.1128/jb.177.5.1268-1274.1995. J Bacteriol. 1995. PMID: 7868601 Free PMC article.

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