Sherman DH - Search Results

1

Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.

Cruz PG, Auld DS, Schultz PJ, Lovell S, Battaile KP, MacArthur R, Shen M, Tamayo-Castillo G, Inglese J, Sherman DH. Cruz PG, et al. Among authors: sherman dh. Chem Biol. 2011 Nov 23;18(11):1442-52. doi: 10.1016/j.chembiol.2011.08.011. Chem Biol. 2011. PMID: 22118678 Free PMC article.

2

The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.

Sherman DH, Li S, Yermalitskaya LV, Kim Y, Smith JA, Waterman MR, Podust LM. Sherman DH, et al. J Biol Chem. 2006 Sep 8;281(36):26289-97. doi: 10.1074/jbc.M605478200. Epub 2006 Jul 6. J Biol Chem. 2006. PMID: 16825192 Free PMC article.

3

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Among authors: sherman dh. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

4

Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.

Kittendorf JD, Beck BJ, Buchholz TJ, Seufert W, Sherman DH. Kittendorf JD, et al. Among authors: sherman dh. Chem Biol. 2007 Aug;14(8):944-54. doi: 10.1016/j.chembiol.2007.07.013. Chem Biol. 2007. PMID: 17719493 Free PMC article.

5

In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.

Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Håkansson K, Thomas CM, Sherman DH. Lopanik NB, et al. Among authors: sherman dh. Chem Biol. 2008 Nov 24;15(11):1175-86. doi: 10.1016/j.chembiol.2008.09.013. Chem Biol. 2008. PMID: 19022178 Free PMC article.

6

Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.

Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Håkansson K, Sherman DH. Buchholz TJ, et al. Among authors: sherman dh. Chem Biol. 2010 Oct 29;17(10):1092-100. doi: 10.1016/j.chembiol.2010.08.008. Chem Biol. 2010. PMID: 21035732 Free PMC article.

7

Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.

Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, Ron D, Sherman DH, Kaufman RJ. Fribley AM, et al. Among authors: sherman dh. J Biomol Screen. 2011 Sep;16(8):825-35. doi: 10.1177/1087057111414893. Epub 2011 Aug 15. J Biomol Screen. 2011. PMID: 21844328 Free PMC article.

8

Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743.

Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller L, Dahlgren M, Kreft R, Yu F, Wolff JJ, Kweon HK, Christiansen MA, Håkansson K, Williams RM, Ehrlich GD, Sherman DH. Rath CM, et al. Among authors: sherman dh. ACS Chem Biol. 2011 Nov 18;6(11):1244-56. doi: 10.1021/cb200244t. Epub 2011 Sep 20. ACS Chem Biol. 2011. PMID: 21875091 Free PMC article.

9

Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.

Li S, Tietz DR, Rutaganira FU, Kells PM, Anzai Y, Kato F, Pochapsky TC, Sherman DH, Podust LM. Li S, et al. Among authors: sherman dh. J Biol Chem. 2012 Nov 2;287(45):37880-90. doi: 10.1074/jbc.M112.410340. Epub 2012 Sep 5. J Biol Chem. 2012. PMID: 22952225 Free PMC article.

10

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

Majmudar CY, Højfeldt JW, Arevang CJ, Pomerantz WC, Gagnon JK, Schultz PJ, Cesa LC, Doss CH, Rowe SP, Vásquez V, Tamayo-Castillo G, Cierpicki T, Brooks CL 3rd, Sherman DH, Mapp AK. Majmudar CY, et al. Among authors: sherman dh. Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11258-62. doi: 10.1002/anie.201206815. Epub 2012 Oct 8. Angew Chem Int Ed Engl. 2012. PMID: 23042634 Free PMC article.

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