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Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.
Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, Ron D, Sherman DH, Kaufman RJ. Fribley AM, et al. Among authors: sherman dh. J Biomol Screen. 2011 Sep;16(8):825-35. doi: 10.1177/1087057111414893. Epub 2011 Aug 15. J Biomol Screen. 2011. PMID: 21844328 Free PMC article.
The role of HTS in drug discovery at the University of Michigan.
Larsen MJ, Larsen SD, Fribley A, Grembecka J, Homan K, Mapp A, Haak A, Nikolovska-Coleska Z, Stuckey JA, Sun D, Sherman DH. Larsen MJ, et al. Among authors: sherman dh. Comb Chem High Throughput Screen. 2014 Mar;17(3):210-30. doi: 10.2174/1386207317666140109121546. Comb Chem High Throughput Screen. 2014. PMID: 24409957 Free PMC article. Review.
Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis.
Sidhu A, Miller JR, Tripathi A, Garshott DM, Brownell AL, Chiego DJ, Arevang C, Zeng Q, Jackson LC, Bechler SA, Callaghan MU, Yoo GH, Sethi S, Lin HS, Callaghan JH, Tamayo-Castillo G, Sherman DH, Kaufman RJ, Fribley AM. Sidhu A, et al. Among authors: sherman dh. ACS Med Chem Lett. 2015 Sep 8;6(11):1122-7. doi: 10.1021/acsmedchemlett.5b00133. eCollection 2015 Nov 12. ACS Med Chem Lett. 2015. PMID: 26617965 Free PMC article.
323 results