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Page 1
Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human Coronaviruses.
Darnotuk ES, Siniavin AE, Shastina NS, Luyksaar SI, Inshakova AM, Bondareva NE, Zolotov SA, Lubenec NL, Sheremet AB, Logunov DY, Zigangirova NA, Gushchin VA, Gintsburg AL. Darnotuk ES, et al. Among authors: sheremet ab. Pharmaceuticals (Basel). 2023 Dec 26;17(1):35. doi: 10.3390/ph17010035. Pharmaceuticals (Basel). 2023. PMID: 38256869 Free PMC article.
Small Molecule Inhibitor of Type Three Secretion System Belonging to a Class 2,4-disubstituted-4H-[1,3,4]-thiadiazine-5-ones Improves Survival and Decreases Bacterial Loads in an Airway Pseudomonas aeruginosa Infection in Mice.
Sheremet AB, Zigangirova NA, Zayakin ES, Luyksaar SI, Kapotina LN, Nesterenko LN, Kobets NV, Gintsburg AL. Sheremet AB, et al. Biomed Res Int. 2018 Sep 10;2018:5810767. doi: 10.1155/2018/5810767. eCollection 2018. Biomed Res Int. 2018. PMID: 30276212 Free PMC article.
A novel antivirulent compound fluorothiazinone inhibits Klebsiella pneumoniae biofilm in vitro and suppresses model pneumonia.
Tsarenko SV, Zigangirova NA, Soloveva AV, Bondareva NE, Koroleva EA, Sheremet AB, Kapotina LN, Shevlyagina NV, Andreevskaya SG, Zhukhovitsky VG, Filimonova EV, Gintsburg AL. Tsarenko SV, et al. Among authors: sheremet ab. J Antibiot (Tokyo). 2023 Jul;76(7):397-405. doi: 10.1038/s41429-023-00621-2. Epub 2023 Apr 21. J Antibiot (Tokyo). 2023. PMID: 37085670
Pharmacokinetics, quorum-sensing signal molecules and tryptophan-related metabolomics of the novel anti-virulence drug Fluorothiazinon in a Pseudomonas aeruginosa-induced pneumonia murine model.
Savitskii MV, Moskaleva NE, Brito A, Zigangirova NA, Soloveva AV, Sheremet AB, Bondareva NE, Lubenec NL, Kuznetsov RM, Samoylov VM, Tagliaro F, Appolonova SA. Savitskii MV, et al. Among authors: sheremet ab. J Pharm Biomed Anal. 2023 Nov 30;236:115739. doi: 10.1016/j.jpba.2023.115739. Epub 2023 Sep 21. J Pharm Biomed Anal. 2023. PMID: 37778200
Study of the Antibacterial Activity of Superhydrophilic and Superhydrophobic Copper Substrates against Multi-Drug-Resistant Hospital-Acquired Pseudomonas aeruginosa Isolates.
Bondareva NE, Sheremet AB, Morgunova EY, Khisaeva IR, Parfenova AS, Chernukha MY, Omran FS, Emelyanenko AM, Boinovich LB. Bondareva NE, et al. Among authors: sheremet ab. Int J Mol Sci. 2024 Jan 8;25(2):779. doi: 10.3390/ijms25020779. Int J Mol Sci. 2024. PMID: 38255852 Free PMC article.
Pharmacokinetics, tissue distribution, bioavailability and excretion of the anti-virulence drug Fluorothiazinon in rats and rabbits.
Savitskii MV, Moskaleva NE, Brito A, Markin PA, Zigangirova NA, Soloveva AV, Sheremet AB, Bondareva NE, Lubenec NL, Tagliaro F, Tarasov VV, Tatzhikova KA, Appolonova SA. Savitskii MV, et al. Among authors: sheremet ab. J Antibiot (Tokyo). 2024 Mar 15. doi: 10.1038/s41429-024-00719-1. Online ahead of print. J Antibiot (Tokyo). 2024. PMID: 38491136
New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses.
Siniavin AE, Gushchin VA, Shastina NS, Darnotuk ES, Luyksaar SI, Russu LI, Inshakova AM, Shidlovskaya EV, Vasina DV, Kuznetsova NA, Savina DM, Zorkov ID, Dolzhikova IV, Sheremet AB, Logunov DY, Zigangirova NA, Gintsburg AL. Siniavin AE, et al. Among authors: sheremet ab. Antiviral Res. 2024 May;225:105871. doi: 10.1016/j.antiviral.2024.105871. Epub 2024 Mar 28. Antiviral Res. 2024. PMID: 38555022 Free article.