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Alternative epidemic indicators for COVID-19 in three settings with incomplete death registration systems.
McCabe R, Whittaker C, Sheppard RJ, Abdelmagid N, Ahmed A, Alabdeen IZ, Brazeau NF, Ahmed Abd Elhameed AE, Bin-Ghouth AS, Hamlet A, AbuKoura R, Barnsley G, Hay JA, Alhaffar M, Koum Besson E, Saje SM, Sisay BG, Gebreyesus SH, Sikamo AP, Worku A, Ahmed YS, Mariam DH, Sisay MM, Checchi F, Dahab M, Endris BS, Ghani AC, Walker PGT, Donnelly CA, Watson OJ. McCabe R, et al. Among authors: sheppard rj. Sci Adv. 2023 Jun 9;9(23):eadg7676. doi: 10.1126/sciadv.adg7676. Epub 2023 Jun 9. Sci Adv. 2023. PMID: 37294754 Free PMC article.
Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context.
Sheppard RJ, Watson OJ, Pieciak R, Lungu J, Kwenda G, Moyo C, Chanda SL, Barnsley G, Brazeau NF, Gerard-Ursin ICG, Olivera Mesa D, Whittaker C, Gregson S, Okell LC, Ghani AC, MacLeod WB, Del Fava E, Melegaro A, Hines JZ, Mulenga LB, Walker PGT, Mwananyanda L, Gill CJ. Sheppard RJ, et al. Nat Commun. 2023 Jun 29;14(1):3840. doi: 10.1038/s41467-023-39288-6. Nat Commun. 2023. PMID: 37380650 Free PMC article.
Author Correction: Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context.
Sheppard RJ, Watson OJ, Pieciak R, Lungu J, Kwenda G, Moyo C, Chanda SL, Barnsley G, Brazeau NF, Gerard-Ursin ICG, Olivera Mesa D, Whittaker C, Gregson S, Okell LC, Ghani AC, MacLeod WB, Del Fava E, Melegaro A, Hines JZ, Mulenga LB, Walker PGT, Mwananyanda L, Gill CJ. Sheppard RJ, et al. Nat Commun. 2024 Mar 12;15(1):2213. doi: 10.1038/s41467-024-44940-w. Nat Commun. 2024. PMID: 38472189 Free PMC article. No abstract available.
Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters.
Casamajo AR, Yu Y, Schnepel C, Morrill C, Barker R, Levy CW, Finnigan J, Spelling V, Westerlund K, Petchey M, Sheppard RJ, Lewis RJ, Falcioni F, Hayes MA, Turner NJ. Casamajo AR, et al. Among authors: sheppard rj. J Am Chem Soc. 2023 Oct 11;145(40):22041-22046. doi: 10.1021/jacs.3c07010. Epub 2023 Oct 2. J Am Chem Soc. 2023. PMID: 37782882 Free PMC article.
Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode.
Lucas SCC, Atkinson SJ, Bamborough P, Barnett H, Chung CW, Gordon L, Mitchell DJ, Phillipou A, Prinjha RK, Sheppard RJ, Tomkinson NCO, Watson RJ, Demont EH. Lucas SCC, et al. Among authors: sheppard rj. J Med Chem. 2020 May 28;63(10):5212-5241. doi: 10.1021/acs.jmedchem.0c00021. Epub 2020 May 6. J Med Chem. 2020. PMID: 32321240 Free article.
A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.
Bamborough P, Chung CW, Demont EH, Bridges AM, Craggs PD, Dixon DP, Francis P, Furze RC, Grandi P, Jones EJ, Karamshi B, Locke K, Lucas SCC, Michon AM, Mitchell DJ, Pogány P, Prinjha RK, Rau C, Roa AM, Roberts AD, Sheppard RJ, Watson RJ. Bamborough P, et al. Among authors: sheppard rj. J Med Chem. 2019 Aug 22;62(16):7506-7525. doi: 10.1021/acs.jmedchem.9b00673. Epub 2019 Aug 9. J Med Chem. 2019. PMID: 31398032
65 results