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Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells.
Haas AR, Golden RJ, Litzky LA, Engels B, Zhao L, Xu F, Taraszka JA, Ramones M, Granda B, Chang WJ, Jadlowsky J, Shea KM, Runkle A, Chew A, Dowd E, Gonzalez V, Chen F, Liu X, Fang C, Jiang S, Davis MM, Sheppard NC, Zhao Y, Fraietta JA, Lacey SF, Plesa G, Melenhorst JJ, Mansfield K, Brogdon JL, Young RM, Albelda SM, June CH, Tanyi JL. Haas AR, et al. Among authors: sheppard nc. Mol Ther. 2023 Aug 2;31(8):2309-2325. doi: 10.1016/j.ymthe.2023.06.006. Epub 2023 Jun 12. Mol Ther. 2023. PMID: 37312454
Swiss army knife T cell: one T cell many tumor targets.
Berjis A, Muthumani D, Sheppard NC, June CH. Berjis A, et al. Among authors: sheppard nc. Cell Res. 2024 Jan;34(1):5-6. doi: 10.1038/s41422-023-00871-7. Cell Res. 2024. PMID: 37666977 No abstract available.
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy.
Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ. Metzloff AE, et al. Among authors: sheppard nc. Adv Mater. 2024 Feb 28:e2313226. doi: 10.1002/adma.202313226. Online ahead of print. Adv Mater. 2024. PMID: 38419362
Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.
Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Liu W, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Hasanali ZS, et al. Among authors: sheppard nc. JCI Insight. 2024 May 7:e177300. doi: 10.1172/jci.insight.177300. Online ahead of print. JCI Insight. 2024. PMID: 38713510 Free article.
Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.
Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Hasanali ZS, et al. Among authors: sheppard nc. bioRxiv [Preprint]. 2024 Jan 24:2024.01.21.576547. doi: 10.1101/2024.01.21.576547. bioRxiv. 2024. PMID: 38328086 Free PMC article. Updated. Preprint.
31 results