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Page 1
Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells.
Davern M, Bracken-Clarke D, Donlon NE, Sheppard AD, Connell FO, Heeran AB, Majcher K, Conroy MJ, Mylod E, Butler C, Donohoe C, Donnell DO, Lowery M, Bhardwaj A, Ravi N, Melo AA, Sullivan JO, Reynolds JV, Lysaght J. Davern M, et al. Among authors: sheppard ad. J Cancer Res Clin Oncol. 2023 Aug;149(9):6583-6599. doi: 10.1007/s00432-023-04620-6. Epub 2023 Feb 15. J Cancer Res Clin Oncol. 2023. PMID: 36790524 Free PMC article.
The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.
Donlon NE, Davern M, Sheppard AD, O'Connell F, Dunne MR, Hayes C, Mylod E, Ramjit S, Temperley H, Mac Lean M, Cotter G, Bhardwaj A, Butler C, Conroy MJ, O'Sullivan J, Ravi N, Donohoe CL, Reynolds JV, Lysaght J. Donlon NE, et al. Among authors: sheppard ad. Front Immunol. 2022 Jan 27;13:823225. doi: 10.3389/fimmu.2022.823225. eCollection 2022. Front Immunol. 2022. PMID: 35154142 Free PMC article.
PD-1 blockade enhances chemotherapy toxicity in oesophageal adenocarcinoma.
Davern M, O' Brien RM, McGrath J, Donlon NE, Melo AM, Buckley CE, Sheppard AD, Reynolds JV, Lynam-Lennon N, Maher SG, Lysaght J. Davern M, et al. Among authors: sheppard ad. Sci Rep. 2022 Feb 28;12(1):3259. doi: 10.1038/s41598-022-07228-x. Sci Rep. 2022. PMID: 35228614 Free PMC article.
PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours.
Davern M, Fitzgerald MC, Buckley CE, Heeran AB, Donlon NE, McGrath J, O' Connell F, Deshpande MR, Hayes C, MacDonald J, Sheppard AD, Reynolds JV, Maher SG, Lynam-Lennon N, Murphy B, Lysaght J. Davern M, et al. Among authors: sheppard ad. Transl Oncol. 2022 May;19:101381. doi: 10.1016/j.tranon.2022.101381. Epub 2022 Mar 1. Transl Oncol. 2022. PMID: 35245832 Free PMC article.
Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma.
Davern M, Donlon NE, O' Connell F, Sheppard AD, Hayes C, King R, Temperley H, Butler C, Bhardwaj A, Moore J, Bracken-Clarke D, Donohoe C, Ravi N, Reynolds JV, Maher SG, Conroy MJ, Lysaght J. Davern M, et al. Among authors: sheppard ad. Transl Oncol. 2022 Jun;20:101406. doi: 10.1016/j.tranon.2022.101406. Epub 2022 Mar 30. Transl Oncol. 2022. PMID: 35366537 Free PMC article.
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients.
Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, Habash M, Sheppard AD, MacLean M, Dunne MR, Moore J, Temperley H, Conroy MJ, Butler C, Bhardwaj A, Ravi N, Donohoe CL, Reynolds JV, Lysaght J. Davern M, et al. Among authors: sheppard ad. Cancer Immunol Immunother. 2023 Jan;72(1):55-71. doi: 10.1007/s00262-022-03228-y. Epub 2022 Jun 16. Cancer Immunol Immunother. 2023. PMID: 35708739 Free PMC article.
Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy.
Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, McGrath J, Sheppard AD, Hayes C, King R, Temperley H, MacLean M, Bulter C, Bhardwaj A, Moore J, Donohoe C, Ravi N, Conroy MJ, Reynolds JV, Lysaght J. Davern M, et al. Among authors: sheppard ad. J Cancer Res Clin Oncol. 2023 Jul;149(8):5377-5395. doi: 10.1007/s00432-022-04440-0. Epub 2022 Nov 29. J Cancer Res Clin Oncol. 2023. PMID: 36445478 Free PMC article.
PD-1 blockade attenuates surgery-mediated immunosuppression and boosts Th1 immunity perioperatively in oesophagogastric junctional adenocarcinoma.
Davern M, Gaughan C, O' Connell F, Moran B, Mylod E, Sheppard AD, Ramjit S, Yun-Tong Kung J, Phelan JJ, Davey MG, Ryan EJ, Butler C, Quinn L, Howard C, Tone E, Phoenix E, Butt WT, Lynam-Lennon N, Maher SG, Ravi N, Donohoe CL, Reynolds JV, Lysaght J, Donlon NE. Davern M, et al. Among authors: sheppard ad. Front Immunol. 2023 Jun 9;14:1150754. doi: 10.3389/fimmu.2023.1150754. eCollection 2023. Front Immunol. 2023. PMID: 37359545 Free PMC article.
30 results