Shepherd TG - Search Results

1

Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells.

Wilson RB, Kozlov AM, Hatam Tehrani H, Twumasi-Ankrah JS, Chen YJ, Borrelli MJ, Sawyez CG, Maini S, Shepherd TG, Cumming RC, Betts DH, Borradaile NM. Wilson RB, et al. Among authors: shepherd tg. J Biol Chem. 2024 Mar;300(3):105684. doi: 10.1016/j.jbc.2024.105684. Epub 2024 Jan 23. J Biol Chem. 2024. PMID: 38272231 Free PMC article.

2

Loss of LKB1-NUAK1 signalling enhances NF-κB activity in a spheroid model of high-grade serous ovarian cancer.

Buensuceso A, Fritz JL, Collins O, Valdés YR, Borrelli MJ, DiMattia GE, Shepherd TG. Buensuceso A, et al. Among authors: shepherd tg. Sci Rep. 2022 Feb 22;12(1):3011. doi: 10.1038/s41598-022-06796-2. Sci Rep. 2022. PMID: 35194062 Free PMC article.

3

A novel role for NUAK1 in promoting ovarian cancer metastasis through regulation of fibronectin production in spheroids.

Fritz JL, Collins O, Saxena P, Buensuceso A, Ramos Valdes Y, Francis KE, Brown KR, Larsen B, Colwill K, Gingras AC, Rottapel R, Shepherd TG. Fritz JL, et al. Among authors: shepherd tg. Cancers (Basel). 2020 May 15;12(5):1250. doi: 10.3390/cancers12051250. Cancers (Basel). 2020. PMID: 32429240 Free PMC article.

4

Inhibiting ULK1 kinase decreases autophagy and cell viability in high-grade serous ovarian cancer spheroids.

Singha B, Laski J, Ramos Valdés Y, Liu E, DiMattia GE, Shepherd TG. Singha B, et al. Among authors: shepherd tg. Am J Cancer Res. 2020 May 1;10(5):1384-1399. eCollection 2020. Am J Cancer Res. 2020. PMID: 32509386 Free PMC article.

5

Mutant p53 murine oviductal epithelial cells induce progression of high-grade serous carcinoma and are most sensitive to simvastatin therapy in vitro and in vivo.

Pereira M, Glogova A, Haagsma J, Stewart J, Shepherd TG, Petrik J. Pereira M, et al. Among authors: shepherd tg. J Ovarian Res. 2023 Nov 20;16(1):218. doi: 10.1186/s13048-023-01307-x. J Ovarian Res. 2023. PMID: 37986175 Free PMC article.

6

AMPK-Independent LKB1 Activity Is Required for Efficient Epithelial Ovarian Cancer Metastasis.

Buensuceso A, Ramos-Valdes Y, DiMattia GE, Shepherd TG. Buensuceso A, et al. Among authors: shepherd tg. Mol Cancer Res. 2020 Mar;18(3):488-500. doi: 10.1158/1541-7786.MCR-19-0530. Epub 2019 Nov 19. Mol Cancer Res. 2020. PMID: 31744879

7

Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids.

Peart T, Ramos Valdes Y, Correa RJ, Fazio E, Bertrand M, McGee J, Préfontaine M, Sugimoto A, DiMattia GE, Shepherd TG. Peart T, et al. Among authors: shepherd tg. Oncotarget. 2015 Sep 8;6(26):22424-38. doi: 10.18632/oncotarget.4211. Oncotarget. 2015. PMID: 26068970 Free PMC article.

8

Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis.

Laski J, Singha B, Wang X, Valdés YR, Collins O, Shepherd TG. Laski J, et al. Among authors: shepherd tg. J Ovarian Res. 2020 May 11;13(1):58. doi: 10.1186/s13048-020-00660-5. J Ovarian Res. 2020. PMID: 32393385 Free PMC article.

9

Gain-of-function p53^R175H blocks apoptosis in a precursor model of ovarian high-grade serous carcinoma.

Haagsma J, Kolendowski B, Buensuceso A, Valdes YR, DiMattia GE, Shepherd TG. Haagsma J, et al. Among authors: shepherd tg. Sci Rep. 2023 Jul 14;13(1):11424. doi: 10.1038/s41598-023-38609-5. Sci Rep. 2023. PMID: 37452087 Free PMC article.

10

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells.

Kim YS, Gupta Vallur P, Jones VM, Worley BL, Shimko S, Shin DH, Crawford LC, Chen CW, Aird KM, Abraham T, Shepherd TG, Warrick JI, Lee NY, Phaeton R, Mythreye K, Hempel N. Kim YS, et al. Among authors: shepherd tg. Oncogene. 2020 Feb;39(8):1619-1633. doi: 10.1038/s41388-019-1097-7. Epub 2019 Nov 13. Oncogene. 2020. PMID: 31723239 Free PMC article.

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