Shepherd PR - Search Results

1

Stratified glucose-lowering response to vildagliptin and pioglitazone by obesity and hypertriglyceridemia in a randomized crossover trial.

Brandon R, Jiang Y, Yeu RQ, Tweedie-Cullen R, Smallman K, Doherty G, Macaskill-Smith KA, Doran RJ, Clark P, Moffitt A, Merry T, Nehren N, King F, Hindmarsh JH, Leask MP, Merriman TR, Orr-Walker B, Shepherd PR, Paul R, Murphy R. Brandon R, et al. Among authors: shepherd pr. Front Endocrinol (Lausanne). 2023 Jan 9;13:1091421. doi: 10.3389/fendo.2022.1091421. eCollection 2022. Front Endocrinol (Lausanne). 2023. PMID: 36699039 Free PMC article. Clinical Trial.

2

A role for β-catenin in diet-induced skeletal muscle insulin resistance.

Masson SWC, Dissanayake WC, Broome SC, Hedges CP, Peeters WM, Gram M, Rowlands DS, Shepherd PR, Merry TL. Masson SWC, et al. Among authors: shepherd pr. Physiol Rep. 2023 Feb;11(4):e15536. doi: 10.14814/phy2.15536. Physiol Rep. 2023. PMID: 36807886 Free PMC article.

3

Conditional Deletion of β-Catenin in the Mediobasal Hypothalamus Impairs Adaptive Energy Expenditure in Response to High-Fat Diet and Exacerbates Diet-Induced Obesity.

Rizwan MZ, Kamstra K, Pretz D, Shepherd PR, Tups A, Grattan DR. Rizwan MZ, et al. Among authors: shepherd pr. J Neurosci. 2024 Apr 3;44(14):e1666232024. doi: 10.1523/JNEUROSCI.1666-23.2024. J Neurosci. 2024. PMID: 38395612

4

Insights into the role of JAK2-I724T variant in myeloproliferative neoplasms from a unique cohort of New Zealand patients.

Puli'uvea C, Immanuel T, Green TN, Tsai P, Shepherd PR, Kalev-Zylinska ML. Puli'uvea C, et al. Among authors: shepherd pr. Hematology. 2024 Dec;29(1):2297597. doi: 10.1080/16078454.2023.2297597. Epub 2024 Jan 10. Hematology. 2024. PMID: 38197452

5

Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin.

Fernando SJA, Wang Q, Hay DL, Bathgate RAD, Shepherd PR, Lee KL. Fernando SJA, et al. Among authors: shepherd pr. Biosci Rep. 2023 Apr 26;43(4):BSR20221956. doi: 10.1042/BSR20221956. Biosci Rep. 2023. PMID: 36947541 Free PMC article.

6

Empowering Pacific Patients on the Weight Loss Surgery Pathway: A Co-designed Evaluation Study.

Taylor TA, Beban G, Yi E, Veukiso M, Sang-Yum G, Dewes O, Wrapson W, Taufa N, Campbell ART, Siegert RJ, Shepherd P. Taylor TA, et al. Obes Surg. 2024 Mar;34(3):959-966. doi: 10.1007/s11695-024-07084-w. Epub 2024 Feb 12. Obes Surg. 2024. PMID: 38345730 Free PMC article.

7

Dietary supplementation of clinically utilized PI3K p110α inhibitor extends the lifespan of male and female mice.

Hedges CP, Shetty B, Broome SC, MacRae C, Koutsifeli P, Buckels EJ, MacIndoe C, Boix J, Tsiloulis T, Matthews BG, Sinha S, Arendse M, Jaiswal JK, Mellor KM, Hickey AJR, Shepherd PR, Merry TL. Hedges CP, et al. Among authors: shepherd pr. Nat Aging. 2023 Feb;3(2):162-172. doi: 10.1038/s43587-022-00349-y. Epub 2023 Jan 23. Nat Aging. 2023. PMID: 37118113

8

Response to BRAF-targeted Therapy Is Enhanced by Cotargeting VEGFRs or WNT/β-Catenin Signaling in BRAF-mutant Colorectal Cancer Models.

Tran KB, Kolekar S, Wang Q, Shih JH, Buchanan CM, Deva S, Shepherd PR. Tran KB, et al. Among authors: shepherd pr. Mol Cancer Ther. 2022 Dec 2;21(12):1777-1787. doi: 10.1158/1535-7163.MCT-21-0941. Mol Cancer Ther. 2022. PMID: 36198029 Free PMC article.

9

The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019.

GBD 2019 Cancer Risk Factors Collaborators. GBD 2019 Cancer Risk Factors Collaborators. Lancet. 2022 Aug 20;400(10352):563-591. doi: 10.1016/S0140-6736(22)01438-6. Lancet. 2022. PMID: 35988567 Free PMC article.

10

β-Cells retain a pool of insulin-containing secretory vesicles regulated by adherens junctions and the cadherin-binding protein p120 catenin.

Dissanayake WC, Shepherd PR. Dissanayake WC, et al. Among authors: shepherd pr. J Biol Chem. 2022 Aug;298(8):102240. doi: 10.1016/j.jbc.2022.102240. Epub 2022 Jul 6. J Biol Chem. 2022. PMID: 35809641 Free PMC article.

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