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Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis.
Shepherd EL, Saborano R, Northall E, Matsuda K, Ogino H, Yashiro H, Pickens J, Feaver RE, Cole BK, Hoang SA, Lawson MJ, Olson M, Figler RA, Reardon JE, Nishigaki N, Wamhoff BR, Günther UL, Hirschfield G, Erion DM, Lalor PF. Shepherd EL, et al. JHEP Rep. 2020 Nov 20;3(2):100217. doi: 10.1016/j.jhepr.2020.100217. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33490936 Free PMC article.
Could endothelial TGFβ signaling be a promising new target for liver disease?
Adams DH, Shepherd EL, Lalor PF. Adams DH, et al. Among authors: shepherd el. Expert Rev Gastroenterol Hepatol. 2018 Jul;12(7):637-639. doi: 10.1080/17474124.2018.1477587. Epub 2018 May 30. Expert Rev Gastroenterol Hepatol. 2018. PMID: 29799279 Free article. No abstract available.
CD151 supports VCAM-1-mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver disease and hepatocellular carcinoma.
Wadkin JCR, Patten DA, Kamarajah SK, Shepherd EL, Novitskaya V, Berditchevski F, Adams DH, Weston CJ, Shetty S. Wadkin JCR, et al. Among authors: shepherd el. Am J Physiol Gastrointest Liver Physiol. 2017 Aug 1;313(2):G138-G149. doi: 10.1152/ajpgi.00411.2016. Epub 2017 May 4. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28473332 Free PMC article.
51 results