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The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.
Li Y, Liu C, Han X, Sheng R, Bao L, Lei L, Wu Y, Li Q, Zhang Y, Zhang J, Wang W, Zhang Y, Li S, Wang C, Wei X, Wang J, Peng Z, Xu Y, Si S. Li Y, et al. Among authors: sheng r. Bioorg Chem. 2024 Jun;147:107364. doi: 10.1016/j.bioorg.2024.107364. Epub 2024 Apr 11. Bioorg Chem. 2024. PMID: 38636434
Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.
He A, Tian S, Kopper O, Horan DJ, Chen P, Bronson RT, Sheng R, Wu H, Sui L, Zhou K, Tao L, Wu Q, Huang Y, Shen Z, Han S, Chen X, Chen H, He X, Robling AG, Jin R, Clevers H, Xiang D, Li Z, Dong M. He A, et al. Among authors: sheng r. PLoS Biol. 2023 Nov 9;21(11):e3002353. doi: 10.1371/journal.pbio.3002353. eCollection 2023 Nov. PLoS Biol. 2023. PMID: 37943878 Free PMC article.
METTL3 Modulates Ctsk+ Lineage Supporting Cranial Osteogenesis via Hedgehog.
Xu R, Sheng R, Lin W, Jiang S, Zhang D, Liu L, Lei K, Li X, Liu Z, Zhang X, Wang Y, Seriwatanachai D, Zhou X, Yuan Q. Xu R, et al. Among authors: sheng r. J Dent Res. 2024 May 16:220345241245033. doi: 10.1177/00220345241245033. Online ahead of print. J Dent Res. 2024. PMID: 38752256
The emerging understanding of Frizzled receptors.
Zheng S, Sheng R. Zheng S, et al. Among authors: sheng r. FEBS Lett. 2024 May 14. doi: 10.1002/1873-3468.14903. Online ahead of print. FEBS Lett. 2024. PMID: 38744670 Review.
545 results