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Plasticizer Interaction With the Heart: Chemicals Used in Plastic Medical Devices Can Interfere With Cardiac Electrophysiology.
Jaimes R 3rd, McCullough D, Siegel B, Swift L, McInerney D, Hiebert J, Perez-Alday EA, Trenor B, Sheng J, Saiz J, Tereshchenko LG, Posnack NG. Jaimes R 3rd, et al. Among authors: sheng j. Circ Arrhythm Electrophysiol. 2019 Jul;12(7):e007294. doi: 10.1161/CIRCEP.119.007294. Epub 2019 Jun 28. Circ Arrhythm Electrophysiol. 2019. PMID: 31248280 Free PMC article.
Experimental factors that impact CaV1.2 channel pharmacology-Effects of recording temperature, charge carrier, and quantification of drug effects on the step and ramp currents elicited by the "step-step-ramp" voltage protocol.
Ren M, Randolph AL, Alvarez-Baron C, Guo D, Tran PN, Thiebaud N, Sheng J, Zhao J, Wu WW. Ren M, et al. Among authors: sheng j. PLoS One. 2022 Nov 23;17(11):e0276995. doi: 10.1371/journal.pone.0276995. eCollection 2022. PLoS One. 2022. PMID: 36417390 Free PMC article.
A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.
Han X, Samieegohar M, Ridder BJ, Wu WW, Randolph A, Tran P, Sheng J, Stoelzle-Feix S, Brinkwirth N, Rotordam MG, Becker N, Friis S, Rapedius M, Goetze TA, Strassmaier T, Okeyo G, Kramer J, Kuryshev Y, Wu C, Strauss DG, Li Z. Han X, et al. Among authors: sheng j. J Pharmacol Toxicol Methods. 2020 Sep;105:106890. doi: 10.1016/j.vascn.2020.106890. Epub 2020 Jun 21. J Pharmacol Toxicol Methods. 2020. PMID: 32574700 Free article.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Ridder BJ, Leishman DJ, Bridgland-Taylor M, Samieegohar M, Han X, Wu WW, Randolph A, Tran P, Sheng J, Danker T, Lindqvist A, Konrad D, Hebeisen S, Polonchuk L, Gissinger E, Renganathan M, Koci B, Wei H, Fan J, Levesque P, Kwagh J, Imredy J, Zhai J, Rogers M, Humphries E, Kirby R, Stoelzle-Feix S, Brinkwirth N, Rotordam MG, Becker N, Friis S, Rapedius M, Goetze TA, Strassmaier T, Okeyo G, Kramer J, Kuryshev Y, Wu C, Himmel H, Mirams GR, Strauss DG, Bardenet R, Li Z. Ridder BJ, et al. Among authors: sheng j. Toxicol Appl Pharmacol. 2020 May 1;394:114961. doi: 10.1016/j.taap.2020.114961. Epub 2020 Mar 21. Toxicol Appl Pharmacol. 2020. PMID: 32209365 Free PMC article.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Ridder BJ, Leishman DJ, Bridgland-Taylor M, Samieegohar M, Han X, Wu WW, Randolph A, Tran P, Sheng J, Danker T, Lindqvist A, Konrad D, Hebeisen S, Polonchuk L, Gissinger E, Renganathan M, Koci B, Wei H, Fan J, Levesque P, Kwagh J, Imredy J, Zhai J, Rogers M, Humphries E, Kirby R, Stoelzle-Feix S, Brinkwirth N, Rotordam MG, Becker N, Friis S, Rapedius M, Goetze TA, Strassmaier T, Okeyo G, Kramer J, Kuryshev Y, Wu C, Himmel H, Mirams GR, Strauss DG, Bardenet R, Li Z. Ridder BJ, et al. Among authors: sheng j. Toxicol Appl Pharmacol. 2020 May 15;395:114983. doi: 10.1016/j.taap.2020.114983. Epub 2020 Apr 2. Toxicol Appl Pharmacol. 2020. PMID: 32247767 Free PMC article. No abstract available.
3,023 results