Shen YA - Search Results

1

Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma.

Trasanidis N, Katsarou A, Ponnusamy K, Shen YA, Kostopoulos IV, Bergonia B, Keren K, Reema P, Xiao X, Szydlo RM, Sabbattini PMR, Roberts IAG, Auner HW, Naresh KN, Chaidos A, Wang TL, Magnani L, Caputo VS, Karadimitris A. Trasanidis N, et al. Among authors: shen ya. Blood. 2022 Mar 31;139(13):1939-1953. doi: 10.1182/blood.2021014391. Blood. 2022. PMID: 35015835 Free article.

2

Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy.

Shen YA, Jung J, Shimberg GD, Hsu FC, Rahmanto YS, Gaillard SL, Hong J, Bosch J, Shih IM, Chuang CM, Wang TL. Shen YA, et al. iScience. 2021 Oct 15;24(11):103297. doi: 10.1016/j.isci.2021.103297. eCollection 2021 Nov 19. iScience. 2021. PMID: 34816098 Free PMC article.

3

Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC).

Hong J, Shen YA, Hsu CY, Huang P, Tomaszewski A, Gabrielson E, Shih IM, Gaillard S, Wang TL. Hong J, et al. Among authors: shen ya. Genes Dis. 2022 Mar 21;9(6):1408-1411. doi: 10.1016/j.gendis.2022.02.009. eCollection 2022 Nov. Genes Dis. 2022. PMID: 36157486 Free PMC article. No abstract available.

4

Novel cancer treatment paradigm targeting hypoxia-induced factor in conjunction with current therapies to overcome resistance.

Kao TW, Bai GH, Wang TL, Shih IM, Chuang CM, Lo CL, Tsai MC, Chiu LY, Lin CC, Shen YA. Kao TW, et al. Among authors: shen ya. J Exp Clin Cancer Res. 2023 Jul 18;42(1):171. doi: 10.1186/s13046-023-02724-y. J Exp Clin Cancer Res. 2023. PMID: 37460927 Free PMC article. Review.

5

PBX1 as a novel master regulator in cancer: Its regulation, molecular biology, and therapeutic applications.

Kao TW, Chen HH, Lin J, Wang TL, Shen YA. Kao TW, et al. Among authors: shen ya. Biochim Biophys Acta Rev Cancer. 2024 Mar;1879(2):189085. doi: 10.1016/j.bbcan.2024.189085. Epub 2024 Feb 8. Biochim Biophys Acta Rev Cancer. 2024. PMID: 38341110 Free article. Review.

6

Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer.

Yu Y, Suryo Rahmanto Y, Shen YA, Ardighieri L, Davidson B, Gaillard S, Ayhan A, Shi X, Xuan J, Wang TL, Shih IM. Yu Y, et al. Among authors: shen ya. EBioMedicine. 2019 Sep;47:184-194. doi: 10.1016/j.ebiom.2019.08.055. Epub 2019 Sep 3. EBioMedicine. 2019. PMID: 31492560 Free PMC article.

7

Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.

Shen YA, Hong J, Asaka R, Asaka S, Hsu FC, Suryo Rahmanto Y, Jung JG, Chen YW, Yen TT, Tomaszewski A, Zhang C, Attarwala N, DeMarzo AM, Davidson B, Chuang CM, Chen X, Gaillard S, Le A, Shih IM, Wang TL. Shen YA, et al. Cancer Res. 2020 Oct 15;80(20):4514-4526. doi: 10.1158/0008-5472.CAN-19-3971. Epub 2020 Aug 28. Cancer Res. 2020. PMID: 32859605 Free PMC article.

8

Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer.

Nguyen T, Kirsch BJ, Asaka R, Nabi K, Quinones A, Tan J, Antonio MJ, Camelo F, Li T, Nguyen S, Hoang G, Nguyen K, Udupa S, Sazeides C, Shen YA, Elgogary A, Reyes J, Zhao L, Kleensang A, Chaichana KL, Hartung T, Betenbaugh MJ, Marie SK, Jung JG, Wang TL, Gabrielson E, Le A. Nguyen T, et al. Among authors: shen ya. Cell Rep. 2019 Apr 9;27(2):491-501.e6. doi: 10.1016/j.celrep.2019.03.036. Cell Rep. 2019. PMID: 30970252 Free PMC article.

9

Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma.

Shen YA, Wang CY, Hsieh YT, Chen YJ, Wei YH. Shen YA, et al. Cell Cycle. 2015;14(1):86-98. doi: 10.4161/15384101.2014.974419. Cell Cycle. 2015. PMID: 25483072 Free PMC article.

10

Therapeutic Targeting of Glutaminolysis as a Novel Strategy to Combat Cancer Stem Cells.

Kao TW, Chuang YC, Lee HL, Kuo CC, Shen YA. Kao TW, et al. Among authors: shen ya. Int J Mol Sci. 2022 Dec 4;23(23):15296. doi: 10.3390/ijms232315296. Int J Mol Sci. 2022. PMID: 36499623 Free PMC article. Review.

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