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Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva.
Williams E, Bagarova J, Kerr G, Xia DD, Place ES, Dey D, Shen Y, Bocobo GA, Mohedas AH, Huang X, Sanderson PE, Lee A, Zheng W, Economides AN, Smith JC, Yu PB, Bullock AN. Williams E, et al. Among authors: shen y. JCI Insight. 2021 Apr 22;6(8):e95042. doi: 10.1172/jci.insight.95042. JCI Insight. 2021. PMID: 33705358 Free PMC article.
Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.
Dey D, Bagarova J, Hatsell SJ, Armstrong KA, Huang L, Ermann J, Vonner AJ, Shen Y, Mohedas AH, Lee A, Eekhoff EM, van Schie A, Demay MB, Keller C, Wagers AJ, Economides AN, Yu PB. Dey D, et al. Among authors: shen y. Sci Transl Med. 2016 Nov 23;8(366):366ra163. doi: 10.1126/scitranslmed.aaf1090. Sci Transl Med. 2016. PMID: 27881824 Free PMC article.
Next-generation probiotic candidates targeting intestinal health in weaned piglets: Both live and heat-killed Akkermansia muciniphila prevent pathological changes induced by enterotoxigenic Escherichia coli in the gut.
Lan C, Li H, Shen Y, Liu Y, Wu A, He J, Cai J, Tian G, Mao X, Huang Z, Yu B, Zheng P, Yu J, Luo J, Yan H, Luo Y. Lan C, et al. Among authors: shen y. Anim Nutr. 2024 Mar 6;17:110-122. doi: 10.1016/j.aninu.2024.01.007. eCollection 2024 Jun. Anim Nutr. 2024. PMID: 38766519 Free PMC article.
Unbiased metastatic niche-labeling identifies estrogen receptor-positive macrophages as a barrier of T cell infiltration during bone colonization.
Xu Z, Liu F, Ding Y, Pan T, Wu YH, Liu J, Bado IL, Zhang W, Wu L, Gao Y, Hao X, Yu L, Edwards DG, Chan HL, Aguirre S, Dieffenbach MW, Chen E, Shen Y, Hoffman D, Dominguez LB, Rivas CH, Chen X, Wang H, Gugala Z, Satcher RL, Zhang XH. Xu Z, et al. Among authors: shen y. bioRxiv [Preprint]. 2024 May 10:2024.05.07.593016. doi: 10.1101/2024.05.07.593016. bioRxiv. 2024. PMID: 38765966 Free PMC article. Preprint.
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