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Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.
Kadur Lakshminarasimha Murthy P, Xi R, Arguijo D, Everitt JI, Kocak DD, Kobayashi Y, Bozec A, Vicent S, Ding S, Crawford GE, Hsu D, Tata PR, Reddy T, Shen X. Kadur Lakshminarasimha Murthy P, et al. Among authors: shen x. Dev Cell. 2022 Feb 7;57(3):310-328.e9. doi: 10.1016/j.devcel.2022.01.006. Dev Cell. 2022. PMID: 35134344 Free PMC article.
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.
Bu P, Wang L, Chen KY, Rakhilin N, Sun J, Closa A, Tung KL, King S, Kristine Varanko A, Xu Y, Huan Chen J, Zessin AS, Shealy J, Cummings B, Hsu D, Lipkin SM, Moreno V, Gümüş ZH, Shen X. Bu P, et al. Among authors: shen x. Nat Commun. 2015 Apr 15;6:6879. doi: 10.1038/ncomms7879. Nat Commun. 2015. PMID: 25872451 Free PMC article.
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Bu P, Chen KY, Xiang K, Johnson C, Crown SB, Rakhilin N, Ai Y, Wang L, Xi R, Astapova I, Han Y, Li J, Barth BB, Lu M, Gao Z, Mines R, Zhang L, Herman M, Hsu D, Zhang GF, Shen X. Bu P, et al. Among authors: shen x. Cell Metab. 2018 Jun 5;27(6):1249-1262.e4. doi: 10.1016/j.cmet.2018.04.003. Epub 2018 Apr 26. Cell Metab. 2018. PMID: 29706565 Free PMC article.
A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.
Somarelli JA, Roghani RS, Moghaddam AS, Thomas BC, Rupprecht G, Ware KE, Altunel E, Mantyh JB, Kim SY, McCall SJ, Shen X, Mantyh CR, Hsu DS. Somarelli JA, et al. Among authors: shen x. Mol Cancer Ther. 2020 Dec;19(12):2516-2527. doi: 10.1158/1535-7163.MCT-20-0454. Epub 2020 Nov 6. Mol Cancer Ther. 2020. PMID: 33158998 Free PMC article.
Mucosal-associated invariant T cell responses differ by sex in COVID-19.
Yu C, Littleton S, Giroux NS, Mathew R, Ding S, Kalnitsky J, Yang Y, Petzold E, Chung HA, Rivera GO, Rotstein T, Xi R, Ko ER, Tsalik EL, Sempowski GD, Denny TN, Burke TW, McClain MT, Woods CW, Shen X, Saban DR. Yu C, et al. Among authors: shen x. Med. 2021 Jun 11;2(6):755-772.e5. doi: 10.1016/j.medj.2021.04.008. Epub 2021 Apr 13. Med. 2021. PMID: 33870241 Free PMC article.
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