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Discovery and extensive in vitro evaluations of NK-HDAC-1: a chiral histone deacetylase inhibitor as a promising lead.
Hou J, Li Z, Fang Q, Feng C, Zhang H, Guo W, Wang H, Gu G, Tian Y, Liu P, Liu R, Lin J, Shi YK, Yin Z, Shen J, Wang PG. Hou J, et al. Among authors: shen j. J Med Chem. 2012 Apr 12;55(7):3066-75. doi: 10.1021/jm201496g. Epub 2012 Mar 30. J Med Chem. 2012. PMID: 22435669
Herein, further SAR studies of lead compound NSC746457 (Shen, J.; Woodward, R.; Kedenburg, J. P.; Liu, X. W.; Chen, M.; Fang, L. Y.; Sun; D. X.; Wang. P. G. J. Med. Chem. 2008, 51, 7417-7427) were performed, including the replacement of the trans-styry …
Herein, further SAR studies of lead compound NSC746457 (Shen, J.; Woodward, R.; Kedenburg, J. P.; Liu, X. W.; Chen, M.; …
Histone deacetylase inhibitors through click chemistry.
Shen J, Woodward R, Kedenburg JP, Liu X, Chen M, Fang L, Sun D, Wang PG. Shen J, et al. J Med Chem. 2008 Dec 11;51(23):7417-27. doi: 10.1021/jm8005355. J Med Chem. 2008. PMID: 19007204 Free PMC article.
The impact of click chemistry in medicinal chemistry.
Hou J, Liu X, Shen J, Zhao G, Wang PG. Hou J, et al. Among authors: shen j. Expert Opin Drug Discov. 2012 Jun;7(6):489-501. doi: 10.1517/17460441.2012.682725. Epub 2012 May 19. Expert Opin Drug Discov. 2012. PMID: 22607210 Review.
A saccharide-based supramolecular hydrogel for cell culture.
Wang W, Wang H, Ren C, Wang J, Tan M, Shen J, Yang Z, Wang PG, Wang L. Wang W, et al. Among authors: shen j. Carbohydr Res. 2011 Jun 1;346(8):1013-7. doi: 10.1016/j.carres.2011.03.031. Epub 2011 Mar 23. Carbohydr Res. 2011. PMID: 21482421
19,540 results
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